Does Thiamine Help Vomiting and Nausea in Pregnancy?
الكلمات الدالة
نبذة مختصرة
وصف
- Research groups: pregnant women eho visit the emergency room for nausea and vomiting in pregnancy, pregnancy age 12 weeks or less
- After basic examinations and hydration, the women will randomized to thiamine or promethazine treatment.
- If no improvement is shown, the patient will be treated with the other drug
- The patients will be interviewed on their current visit and every two weeks until 14th week of gestation
- The interview includes medical history and details about their illness, other treatments, hospitalization etc.
تواريخ
| آخر التحقق: | 05/31/2015 |
| تم الإرسال لأول مرة: | 02/17/2009 |
| تم إرسال التسجيل المقدر: | 03/11/2009 |
| أول نشر: | 03/12/2009 |
| تم إرسال آخر تحديث: | 06/20/2015 |
| آخر تحديث تم نشره: | 06/22/2015 |
| تاريخ بدء الدراسة الفعلي: | 01/31/2009 |
| تاريخ الإنجاز الأساسي المقدر: | 12/31/2011 |
| التاريخ المتوقع لانتهاء الدراسة: | 12/31/2011 |
حالة أو مرض
التدخل / العلاج
Drug: thiamine & promethazine
مرحلة
مجموعات الذراع
| ذراع | التدخل / العلاج |
|---|---|
| Active Comparator: 1. thiamine Pregnant women until 12 week of gestation who refer to the ER because of nausea and vomiting and didn't improve after hydration, will receive thiamine IV | |
| Active Comparator: 2. promethazine Pregnant women until 12 week of gestation who refer to the ER because of nausea and vomiting and didn't improve after hydration, will receive promethazine IV |
معايير الأهلية
| الأعمار المؤهلة للدراسة | 18 Years إلى 18 Years |
| الأجناس المؤهلة للدراسة | Female |
| يقبل المتطوعين الأصحاء | نعم |
| المعايير | Inclusion Criteria: - Pregnant women until 12th week of gestation - The women visit the ER because of nausea and vomiting - The women didn't received thiamine yet Exclusion Criteria: - Pregnant women over 12th week of gestation - Women that received thiamine before - women that allergic to the studied drugs |
النتيجة
مقاييس النتائج الأولية
1. the improvement in nausea and/or vomiting after treatment [2 months after first visit in ER (until 14 week of pregnancy)]
