The Acute Effects of Oleic Acid Enriched-diets on Lipids, Insulin Sensitivity and Serum Inflammatory Markers
الكلمات الدالة
نبذة مختصرة
وصف
A randomized, single blind, crossover design was undertaken to test meals enriched with palm olein vs olive oil vs lard. Volunteers were asked to participate in three postprandial challenges, separated by at least 3-days. Subjects were provided a low fat meal(<10g fat) the day before the intervention. Fasting blood was collected the next day and the subjects were instructed to consume test meals (50g high fat meal). Further venous blood was collected at 30 min, 1h, 2h, 3h and 4h postprandially.
Primary outcome variable: Triacylglycerol (TAG) Secondary outcome variables: Insulin sensitivity (glucose, insulin), non esterified fatty acids (NEFA), inflammatory markers
تواريخ
| آخر التحقق: | 04/30/2010 |
| تم الإرسال لأول مرة: | 05/11/2010 |
| تم إرسال التسجيل المقدر: | 05/13/2010 |
| أول نشر: | 05/16/2010 |
| تم إرسال آخر تحديث: | 05/13/2010 |
| آخر تحديث تم نشره: | 05/16/2010 |
| تاريخ بدء الدراسة الفعلي: | 07/31/2009 |
| تاريخ الإنجاز الأساسي المقدر: | 08/31/2009 |
| التاريخ المتوقع لانتهاء الدراسة: | 08/31/2009 |
حالة أو مرض
التدخل / العلاج
Dietary Supplement: The acute effects of dietary fat on lipid profile, insulin sensitivity and inflammatory markers
مرحلة
مجموعات الذراع
| ذراع | التدخل / العلاج |
|---|---|
| Experimental: palm olein | |
| Experimental: olive oil | |
| Experimental: lard |
معايير الأهلية
| الأعمار المؤهلة للدراسة | 18 Years إلى 18 Years |
| الأجناس المؤهلة للدراسة | Male |
| يقبل المتطوعين الأصحاء | نعم |
| المعايير | Inclusion Criteria: - Age: 18-45 years - BMI : 18.5-30 kg/m^2 - Healthy, men Exclusion Criteria: - medical history of cardiovascular disease, cancer, diabetes or chronic diseases - BMI < 18.5 OR > 30 kg/m^2 - waist hip ratio > 0.9 - total cholesterol > 5.2 mmol/L - triacylglycerol (TAG) > 2.2 mmol/L - current use of antihypertensive or lipid lowering medication |
النتيجة
مقاييس النتائج الأولية
1. Triacylglycerol (TAG) [4 h]
مقاييس النتائج الثانوية
1. Insulin sensitivity (glucose, insulin), non-esterified fatty acids (NEFA), inflammatory markers [4 h]
