atractylodin/atractylodes

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Determination and Pharmacokinetic Comparisons of Atractylodin after Oral Administration of Crude and Processed Atractylodis rhizoma.

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BACKGROUND In traditional Chinese medicine, Atractylodis rhizoma is the dried rhizome of Atractylodes lancea (Thunb.) DC. or Atractylodes chinensis (DC.) Koidz. After being processed, the dryness of A. rhizoma decreased, and the function of tonifying spleen increased. Therefore, the processed A.

Determination and Tissue Distribution Comparisons of Atractylodin after Oral Administration of Crude and Processed Atractylodes Rhizome.

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BACKGROUND Atractylodis rhizoma is one of the most often used drugs in traditional Chinese medicine. Stir frying with wheat bran is the most common processing method. To clarify the principle of processing, an experiment was carried out to compare the tissue distribution of typical constituent after

A new 9-nor-atractylodin from Atractylodes lancea and the antibacterial activity of the atractylodin derivatives.

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A new compound, namely, 9-nor-atractylodin (1) and one known atractylodin (2) were isolated from the rhizomes of Atractylodes lancea. The structural modifications of atractylodin were carried out and a series of atractylodin derivatives (3-10) were obtained. The antibacterial activities of 1-10 were

[Effect of endophytic fungal elicitors on growth and atractylodin accumulation of cell suspension cultures of Atractylodes lancea].

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OBJECTIVE To investigate the effects of endophytic fungal elicitors on the growth and atractylodin accumulation of cell suspension cultures of Atractylodes lancea. METHODS The endophytic fungal elicitors were added to the medium with different concentrations and culture period. Their effects on

Antiinflammatory constituents of Atractylodes chinensis rhizome improve glomerular lesions in immunoglobulin A nephropathy model mice.

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The crude drug Sojutsu, as defined by the Japanese Pharmacopoeia, is the rhizome of Atractylodes lancea De Candolle, Atractylodes chinensis Koidzumi, or their interspecific hybrids (Asteraceae). Sojutsu is one of the traditional Kampo formulas, which are administered to patients suffering from

[Simultaneous determination of polyacetylene components in Cangzhu by reversed-phase high performance liquid chromatography].

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In traditional Chinese medicines, atractylodes rhizome ("Cangzhu" in Chinese) is used for the treatment of rheumatic diseases, digestive disorders, mild diarrhea, night-blindness. According to the Pharmacopoeia of China (2005 Edition), Rhizoma Atractylodis is the dried root of Atractylodes lancea

A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis.

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To clarify the variation in the pharmacologically active components of the essential oil contained in the rhizomes of Atractylodes lancea and A. chinensis growing in China, we transplanted the rhizomes of the wild plants from 18 populations, including A. koreana, in the same experimental field.

Genetic and environmental factors influencing the contents of essential oil compounds in Atractylodes lancea.

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Rhizomes of Atractylodes lancea are used in traditional Japanese medicine (Kampo) and Chinese medicine to treat numerous diseases and disorders because they contain many pharmacologically active compounds. The major active compounds in A. lancea are essential oil compounds such as β-eudesmol,

Lipase inhibition and antiobesity effect of Atractylodes lancea.

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The ethanol extract of Atractylodes lancea rhizome displayed significant lipase inhibition with an IC50 value of 9.06 µg/mL in a human pancreatic lipase assay from high-throughput screening. Bioassay-guided isolation led to the identification of one new polyacetylene,

Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants.

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Total DNAs were prepared from the leaves of Atractylodes lancea DE CANDOLLE, A. chinensis KOIDZUMI, A. lancea var. simplicifolia KITAMURA, A. japonica KOIDZUMI ex KITAMURA and A. ovata DE CANDOLLE. The DNAs were subjected to random amplified polymorphic DNA (RAPD) analysis. Some primers showed the

Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures.

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Two strains of autotetraploid plants of Atractylodes lancea DC. (Compositae) were raised from the in vitro colchicine-treated shoot cultures, and field trials were performed to evaluate their growth and the amount of essential oil components in the rhizome in comparison with the corresponding

Further phenols and polyacetylenes from the rhizomes of Atractylodes lancea and their anti-inflammatory activity.

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From the rhizomes of Atractylodes lancea, 2-[(2'E)-3',7'-dimethyl-2',6'-octadienyl]-4-methoxy-6-methylphenol (1) was isolated as a new natural product. The compound showed strong inhibitory effects on 5-lipoxygenase (5-LOX) and cyclooxygenase-1 (COX-1), but exhibited only weak antioxidative

[Simultaneous determination of atractylone, hinesol, beta-eudesmol, atrctylodin in Atractylodes lancea and hierarchical cluster analysis].

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OBJECTIVE To develop a GC method for simultaneous determination of 4 compounds (atractylone, hinesol, beta-eudesmol and atractylodin) in Atractylodes lancea. METHODS A HP-1 capillary column (0.25 mm x 30 m, 0.25 microm) was used. The detector was FID:Inlet temperature was 250 degrees C. The detector

[The naphtha composing characteristics of geoherbs of Atractylodes lancea].

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OBJECTIVE To find the chemical diversity and characteristics of A. lancea on two levels--individuals and populations, and to discover the chemical essentials for forming geoherbs. METHODS 47 rhizomes of A. lancea were collected in 7 populations, and 6 naphtha components (1. elemol, 2. hinesol, 3.

[Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea].

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OBJECTIVE To investigate the effects of different amounts of lime on yield and quality of Atractylodes lancea, and to provide reference for the herb growing site soil improvement and self-poisoning ease. METHODS Add different gradients of lime, and then measure their growth targets, yield and four

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