hinesol/atractylodes

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Biotransformation of hinesol isolated from the crude drug Atractylodes lancea by Aspergillus niger and Aspergillus cellulosae.

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Biotransformation of the sesquiterpene alcohol hinesol (1) with spasmolytic activity, which was prepared from the rhizome of Atractylodes lancea, was carried out by Aspergillus niger and Aspergillus cellulosae IFO 4040. Compound 1 was easily converted to compounds 2-9 by A. niger, and compounds 10

Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells.

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Hinesol is a unique sesquiterpenoid isolated from the Chinese traditional medicine, Atractylodes lancea rhizome. In a previous study, we screened various natural products in human leukemia HL-60 cells and identified an essential oil fraction from A. lancea rhizome that exhibited apoptosis-inducing

Evaluation of heritability of β-eudesmol/hinesol content ratio in Atractylodes lancea De Candolle.

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Atractylodes lancea De Candolle is a medicinal plant distributed in East Asia. Its rhizome has been used as an important crude drug in traditional Chinese and Japanese medicines for the treatment of numerous diseases and disorders. In recent years, the demand for mass production of the

[Simultaneous determination of atractylone, hinesol, beta-eudesmol, atrctylodin in Atractylodes lancea and hierarchical cluster analysis].

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OBJECTIVE To develop a GC method for simultaneous determination of 4 compounds (atractylone, hinesol, beta-eudesmol and atractylodin) in Atractylodes lancea. METHODS A HP-1 capillary column (0.25 mm x 30 m, 0.25 microm) was used. The detector was FID:Inlet temperature was 250 degrees C. The detector

The antitumor effect of hinesol, extract from Atractylodes lancea (Thunb.) DC. by proliferation, inhibition, and apoptosis induction via MEK/ERK and NF-κB pathway in non-small cell lung cancer cell lines A549 and NCI-H1299.

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Lung cancer (especially, non-small cell lung cancer [NSCLC]) is one of the most malignant cancers in the world. Hinesol is the major component of the essential oil of Atractylodes lancea (Thunb.) DC and possesses the most promising anticancer function. However, the effects and molecular mechanism of

Studies on the constituents of atractylodes. X. Correlation of hinesol and beta-vetivone.

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Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis.

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BACKGROUND In a screening programme for new agrochemicals from Chinese medicinal herbs, the essential oil of Atractylodes chinensis (DC.) Koidz was found to possess strong insecticidal activity against the common vinegar fly, Drosophila melanogaster L. The essential oil was extracted via

Antiinflammatory constituents of Atractylodes chinensis rhizome improve glomerular lesions in immunoglobulin A nephropathy model mice.

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The crude drug Sojutsu, as defined by the Japanese Pharmacopoeia, is the rhizome of Atractylodes lancea De Candolle, Atractylodes chinensis Koidzumi, or their interspecific hybrids (Asteraceae). Sojutsu is one of the traditional Kampo formulas, which are administered to patients suffering from

Antioxidant, antimicrobial and anti-inflammatory activities of essential oil derived from the wild rhizome of Atractylodes macrocephala Koidz

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The present study investigated the chemical composition, antioxidant, antimicrobial, and anti-inflammatory activities of essential oil (EO) derived from the wild rhizomes of Atractylodes macrocephala Koidz (AMA) growing in Qimen County (eastern China). GC-MS analysis identified fifteen compounds,

A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis.

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To clarify the variation in the pharmacologically active components of the essential oil contained in the rhizomes of Atractylodes lancea and A. chinensis growing in China, we transplanted the rhizomes of the wild plants from 18 populations, including A. koreana, in the same experimental field.

[Study of components in crude drugs by headspace gas chromatography. II. Components of atractylodes].

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Determination of volatile components in essential oils from Atractylodis plants was studied by headspace gas chromatography. The crude drug of 0.20 g with 1.0 ml of water in a capped vial was heated at 130 degrees C for 45 min. Then 0.5 ml of vaporized components were collected by gas tightsillinge,

Seven herbs against the stored product insect: Toxicity evidence and the active sesquiterpenes from Atractylodes lancea.

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In this work, the essential oils (EO) were extracted from seven typical Chinese herbs, and their repellent and contact toxicities against Tribolium castaneum adults (red flour beetles) were evaluated. The experimental results showed that the above EOs presented the various levels of repellent and

[Studies on chemical constituents in essential oil from wild Atractylodes lancea in dabie mountains].

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The chemical constituents in essential oil of wild Atractylodes lancea (Thumb.) DC. from Dabie Mountains were studied. The essential oil was extracted by simultaneous distillation and extraction equipment and analyzed by gas chromatography-mass spectrometry method. 49 compounds were identified and

[GC-MS analysis of essential oils from rhizomes of Atractylodes lancea (Thunb.) DC. and A. chinensis (DC.) Koidz].

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OBJECTIVE To analyze the constituents from the rhizomes of Atractylodes lancea and A. chinensis in essential oils. METHODS GC-MS method was used. RESULTS 32 and 29 compounds were identified respectively. CONCLUSIONS The main constituents in the essential oils from the rhizome of A. chinensis are

Genetic and environmental factors influencing the contents of essential oil compounds in Atractylodes lancea.

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Rhizomes of Atractylodes lancea are used in traditional Japanese medicine (Kampo) and Chinese medicine to treat numerous diseases and disorders because they contain many pharmacologically active compounds. The major active compounds in A. lancea are essential oil compounds such as β-eudesmol,

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