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Spectrum of acute cortical necrosis in Indian patients.

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Forty-nine out of 662 patients (7.4%) dialysed for acute renal failure were found to have bilateral renal cortical necrosis. Amongst 6061 autopsies carried out in our centre during the same period, the incidence of cortical necrosis was 0.7%. Obstetric causes were responsible for the renal lesion in

Curcumin: the Indian solid gold.

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Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in the Indian subcontinent, not only for health care but also for the preservation of food and as a yellow dye for textiles. Curcumin, which gives the yellow color to turmeric, was first isolated almost two

Hepatic trauma: an Indian experience.

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Over a five year period, between January 1989 and December 1993, a total of 230 patients with confirmed hepatic injuries were treated at a major urban trauma center. The mechanism of injury was blunt in 154 patients (67%). Nonoperative treatment was given in 18 patients (8%). All operated patients

High nucleotide and amino acid sequence similarities in tumour necrosis factor-alpha amongst Indian buffalo (Bubalus bubalis), Indian cattle (Bos indicus) and other ruminants.

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Tumour necrosis factor-alpha (TNF-alpha) mRNA from Indian water buffalo (Bubalus bubalis) and Indian cattle (Bos indicus) was reverse transcribed and amplified using reverse transcriptase-polymerase chain reaction (RT-PCR). The nucleotide sequences of cDNAs were determined after cloning into

The Indian Consensus Document on cardiac biomarker.

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Despite recent advances, the diagnosis and management of heart failure evades the clinicians. The etiology of congestive heart failure (CHF) in the Indian scenario comprises of coronary artery disease, diabetes mellitus and hypertension. With better insights into the pathophysiology of CHF,

Radiofrequency tissue ablation: an early Indian experience.

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BACKGROUND Radiofrequency (RF) tissue ablation has been tried safely and effectively in the West as percutaneous local tissue ablation therapy. We present our experience with this technique in malignant lesions. METHODS RF tumor ablation was done using an RF generator (Berchtold; Germany) generating

Acute renal failure in north Indian children.

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The spectrum and outcome of acute renal failure (ARF) were studied in 205 children aged between 1 month and 12 yr. There were 145 boys and 60 girls; 23 per cent were below 1 yr and 49 per cent between 1 and 4 yr. The main causes of ARF were haemolytic uraemic syndrome (HUS) in 36 per cent, serious

Induction of tumours by Indian dietary constituents.

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Fishes and vegetables are preserved by salting and sundrying; and later fried in oil and consumed. Such preparations have been found to contain polycyclic aromatic hydrocarbons, and are genotoxic and mutagenic. The potential carcinogenic effects of these and other dietary items have been studied by

Chronic hepatitis in a large Indian hospital.

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BACKGROUND In developed countries as well as in Southeast Asia, the hepatitis B and C viruses are the main causes of chronic hepatitis. In India, however, there have been no major investigations on the aetiology of chronic hepatitis. (The hepatitis E virus which is responsible for half the sporadic

Management of massive haemobilia in an Indian hospital.

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BACKGROUND Massive haemobilia carries a mortality of 25% in most reports. Although previously it was mainly due to road accidents or homicidal attempts it is now more often due to iatrogenic trauma like percutaneous liver biopsy and biliary drainage. However the management protocol is not

Tumor necrosis factor-alpha microsatellite polymorphism association with rheumatoid arthritis in Indian patients.

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BACKGROUND Level of TNF-alpha increases significantly in synovial fluid of rheumatoid arthritis (RA) patients. It is proposed that tumor necrosis factor (TNF) microsatellite alleles may influence its expression and presumably can contribute to the disease severity. However, there is a lack of such

Island pectoralis major myocutaneous flap: an Indian perspective.

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The aim of this study is to conceive a method of raising an island PMMC flap, so as to circumvent its drawbacks of bulk, flap length and the difficulty of developing this flap in female patients. And to consider island PMMC flap as a viable reconstructive option in head and neck surgeries,

Pulse cyclophospamide in severe lupus nephritis: Southern Indian experience.

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To evaluate the efficacy and safety of the monthly pulse IV cyclophosphamide (IVC) therapy in patients with severe lupus nephritis, we studied 39 patients of lupus nephritis on IVC therapy between 1998 to 2002. Single monthly cyclophosphamide (0.75-1 g/m(2)) was infused intravenously with oral

Autoimmune hepatitis in the Indian subcontinent: 7 years experience.

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BACKGROUND Autoimmune hepatitis (AIH) is presumed to be rare in India. The present prospective study was carried out to determine the prevalence, clinical, biochemical and histological profile of patients with AIH in India. METHODS Consecutive patients with chronic liver disease suspected to be AIH,

Idiopathic inflammatory myopathy: clinicopathological observations in the Indian population.

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The present study attempts to investigate the pathological basis of the two clinically different forms of idiopathic inflammatory myopathy (IIM) namely, polymyositis (PM) and dermatomyositis (DM). Clinicopathological analysis of 73 cases showed that muscle fibre necrosis and regeneration were more

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