Pain Sensitivity in NREM Parasomnia (NOCISOMNIE)
Açar sözlər
Mücərrəd
Tarixlər
Son Doğrulandı: | 05/31/2018 |
İlk təqdim: | 09/05/2016 |
Təxmini qeydiyyat təqdim edildi: | 09/13/2016 |
İlk Göndərmə: | 09/19/2016 |
Son Yeniləmə Göndərildi: | 06/06/2018 |
Son Yeniləmə Göndərildi: | 06/10/2018 |
Həqiqi Təhsilin Başlama Tarixi: | 09/30/2015 |
Təxmini İlkin Tamamlanma Tarixi: | 09/30/2017 |
Təxmini İşin Tamamlanma Tarixi: | 09/30/2017 |
Vəziyyət və ya xəstəlik
Müdaxilə / müalicə
Other: CASE (adult sleepwalking patients)
Other: CONTROL (adult healthy volunteers)
Faza
Qol Qrupları
Qol | Müdaxilə / müalicə |
---|---|
Experimental: CASE (adult sleepwalking patients) | Other: CASE (adult sleepwalking patients) 24-hour sleep deprivation protocol, polysomnographic monitoring of the recovery sleep, triggering of parasomniac episodes by auditory stimulations, thermoalgic stimulation (Modulator Sensory Analyzer Thermal Stimulator®) during wakefulness, parasomniac episodes, NREM stage 2 ans SWS |
Experimental: CONTROL (adult healthy volunteers) | Other: CONTROL (adult healthy volunteers) 24-hour sleep deprivation protocol, polysomnographic monitoring of the recovery sleep, thermoalgic stimulation (Modulator Sensory Analyzer Thermal Stimulator®) during wakefulness, NREM stage 2 ans SWS |
Uyğunluq Kriteriyaları
Təhsil üçün uyğun yaşlar | 18 Years Üçün 18 Years |
Təhsilə Uyğun Cinslər | All |
Sağlam Könüllüləri qəbul edir | Bəli |
Kriteriyalar | Inclusion Criteria: - Subject from 18 years-old to 45 years-old - Affiliated to social security - Written informed consent * CASE specific inclusion criteria : - NREM parasomnia diagnosed according to the International Classification of Sleep Disorders 3rd edition (ICSD-3) criteria and confirmed by polysomnography assessment - Frequent symptomatology (at least 1 episode by week in the past 3 months) * CONTROL specific inclusion criteria : - No medical history of NREM parasomnia Exclusion Criteria: - Known skin allergy to metal - Use of psychotropic drugs during the 15 days before the inclusion - Use of analgesic drugs during the 15 days before the inclusion - A diagnosis of sleep apnea syndrome, periodic limb movements or restless legs syndrome present more than twice a week - Medical history of epilepsy - Non stable psychiatric disorder - Pregnancy, breastfeeding - Subject deprived of liberty or protected by law (tutorship, curatorship). |
Nəticə
İlkin nəticə tədbirləri
1. Percentage of neurophysiological arousal response within 5 seconds after a subthreshold thermoalgic stimulation applied during parasomniac episodes. [within 5 seconds after stimulation]
İkincili Nəticə Tədbirləri
1. Temperature of the thermoalgic stimulation during wakefulness associated with a nociceptive perception of 5/10 on a visual analogic scale [on inclusion]
2. Minimal temperature of thermoalgic stimulations associated with a neurophysiological arousal response in NREM sleep stage 2 [within 5 seconds]
3. Nociceptive behavioural response [within 5 seconds after a subthreshold thermoalgic stimulations applied during sleep and parasomniac episodes]