Randomised Comparison of 2 Cold Snare Polypectomy Techniques
Yalnız qeydiyyatdan keçmiş istifadəçilər məqalələri tərcümə edə bilərlər
Giriş / Qeydiyyatdan keçin
Bağlantı panoya saxlanılır
StatusTamamlandı
Sponsorlar
Sheffield Teaching Hospitals NHS Foundation Trust
KLINIK SINAQ: NCT02208401
BioSeek: NCT02208401
Açar sözlər
Mücərrəd
Different modalities are employed to remove small colonic polyps which potentially harbour a cancer risk. But, they can all vary in their completeness of removal, safety and the histological quality and the gold standard technique has yet to be defined. A novel suction pseudopolyp technique has been described by Patullo et al and in their prospective study, 126 polyps measuring less than 10mm flat or sessile were removed by this method with 100% complete endoscopic resection and without any immediate or delayed complications. The aim of the investigators study is to compare this technique with the standard cold snare technique. Patients attending for a routine colonoscopy and found to have polyps measuring 37mm in size will be eligible and they will be randomised to the polypectomy technique. Patient demographics and polyp characteristics will be recorded. The primary outcome measured will be the macroscopic resection rate. The secondary outcome measures are abdominal pain, tenderness, bleeding and fever.
Tarixlər
Son Doğrulandı: | 07/31/2014 |
İlk təqdim: | 07/29/2014 |
Təxmini qeydiyyat təqdim edildi: | 08/03/2014 |
İlk Göndərmə: | 08/04/2014 |
Son Yeniləmə Göndərildi: | 08/11/2014 |
Son Yeniləmə Göndərildi: | 08/12/2014 |
Həqiqi Təhsilin Başlama Tarixi: | 12/31/2013 |
Təxmini İlkin Tamamlanma Tarixi: | 07/31/2014 |
Təxmini İşin Tamamlanma Tarixi: | 07/31/2014 |
Vəziyyət və ya xəstəlik
Bowel Cancer
Müdaxilə / müalicə
Procedure: conventional cold snare polypectomy
Procedure: Cold snare polypectomy with suction
Faza
-
Qol Qrupları
Qol | Müdaxilə / müalicə |
---|---|
Active Comparator: conventional cold snare polypectomy conventional cold snare polypectomy | Procedure: conventional cold snare polypectomy conventional cold snare polypectomy |
Experimental: Cold snare polypectomy with suction Cold snare polypectomy with suction | Procedure: Cold snare polypectomy with suction Cold snare polypectomy with suction |
Uyğunluq Kriteriyaları
Təhsil üçün uyğun yaşlar | 18 Years Üçün 18 Years |
Təhsilə Uyğun Cinslər | All |
Sağlam Könüllüləri qəbul edir | Bəli |
Kriteriyalar | Inclusion Criteria: - All patients with small polyps 3-7 mm in size, flat or sessile found during colonoscopy Exclusion Criteria: - Patients are less than 18 years old - Pregnant - Inadequate bowel preparation - On anticoagulants or clopidogrel |
Nəticə
İlkin nəticə tədbirləri
1. Complete macroscopic polyp eradication rate [At time of polypectomy intervention]
The primary outcome for this study is the polypectomy completion rate. This will be assessed both macroscopically and histologically. The analysis for statistical difference between the 2 techniques and abdominal symptoms will be compared by the Chi2 test for categorical data.