Analgesic Effects of Gabapentin and Paracetamol
Açar sözlər
Mücərrəd
Təsvir
Gabapentin is an anti-convulsion medication and has a high affinity for voltage-gated calcium channel throughout the brain, acts by inhibition of release of excitatory neurotransmitters. As a lipophilic substance, it shows linear pharmacokinetics and has oral bioavailability greater than 90%. Gabapentin is used in a variety of condition as a therapeutic measure involving diabetic neuropathy, post-herpetic neuralgia, in partial seizures, restless leg syndrome, post-menopausal hot flashes, anxiety, resistant mood disorders, essential tremors, and numerous other modalities. Gabapentin is a muscle relaxant and anti-spasmodic, its analgesic effect has also be identified for moderate to severe pain.
Tarixlər
Son Doğrulandı: | 12/31/2019 |
İlk təqdim: | 11/10/2018 |
Təxmini qeydiyyat təqdim edildi: | 08/22/2019 |
İlk Göndərmə: | 08/27/2019 |
Son Yeniləmə Göndərildi: | 01/21/2020 |
Son Yeniləmə Göndərildi: | 01/26/2020 |
Həqiqi Təhsilin Başlama Tarixi: | 08/31/2019 |
Təxmini İlkin Tamamlanma Tarixi: | 01/06/2020 |
Təxmini İşin Tamamlanma Tarixi: | 01/20/2020 |
Vəziyyət və ya xəstəlik
Müdaxilə / müalicə
Drug: Gabapentin 600 mg Tab
Faza
Qol Qrupları
Qol | Müdaxilə / müalicə |
---|---|
Experimental: Group A Gabapentin 600 mg Tab | |
Active Comparator: Group B Paracetamol 1000 mg Tab |
Uyğunluq Kriteriyaları
Təhsil üçün uyğun yaşlar | 18 Years Üçün 18 Years |
Təhsilə Uyğun Cinslər | All |
Sağlam Könüllüləri qəbul edir | Bəli |
Kriteriyalar | 1. Inclusion Criteria: 1. Patients between 18-60 years of age 2. Patients Undergoing hand surgery in the Department of Plastics and Reconstructive Surgery, Dr. Ruth KM Pfau Civil Hospital Karachi, Dow University of Health Sciences 2. Exclusion criteria: 1. Pregnant women 2. Any patient presenting with the signs of: - Arrhythmia - Myocardial ischemia - Cognitive impairment - Psychiatric disorders - Drug abuse 3. Patients sensitive to any epileptic drug or taking any anti-epileptic drug 4. Having severe and multiple injuries. |
Nəticə
İlkin nəticə tədbirləri
1. Comparison of analgesic effects of Gabapentin and paracetamol in patients with hand injury [6 months]