Effectiveness of Two Water-Based Potassium Oxalate Desensitizers

Yalnız qeydiyyatdan keçmiş istifadəçilər məqalələri tərcümə edə bilərlər

Giriş / Qeydiyyatdan keçin

Bağlantı panoya saxlanılır

StatusTamamlandı

Sponsorlar

Procter and Gamble

KLINIK SINAQ: NCT02192307

BioSeek: nct02192307

Açar sözlər

Mücərrəd

This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.

Tarixlər

Son Doğrulandı:	09/30/2019
İlk təqdim:	07/13/2014
Təxmini qeydiyyat təqdim edildi:	07/13/2014
İlk Göndərmə:	07/15/2014
Son Yeniləmə Göndərildi:	10/16/2019
Son Yeniləmə Göndərildi:	11/04/2019
İlk təqdim edilmiş nəticələrin tarixi:	08/29/2019
İlk təqdim edilmiş QC nəticələrinin tarixi:	10/16/2019
İlk göndərilən nəticələrin tarixi:	11/04/2019
Həqiqi Təhsilin Başlama Tarixi:	06/30/2014
Təxmini İlkin Tamamlanma Tarixi:	08/31/2014
Təxmini İşin Tamamlanma Tarixi:	08/31/2014

Vəziyyət və ya xəstəlik

Dentin Sensitivity

Müdaxilə / müalicə

Device: Potassium oxalate

Faza

Qol Qrupları

Qol	Müdaxilə / müalicə
Experimental: potassium oxalate gel Professional application
Active Comparator: Potassium oxalate liquid Professional application

Uyğunluq Kriteriyaları

Təhsil üçün uyğun yaşlar	18 Years Üçün 18 Years
Təhsilə Uyğun Cinslər	All
Sağlam Könüllüləri qəbul edir	Bəli
Kriteriyalar	Inclusion Criteria: - Provide written informed consent to participate in the study - Be at least 18 years of age - Be in good general health, as determined by the Investigator/designee based on review of the health history/update for participation in the study - Agree to refrain from participating in any other oral/dental product studies for the duration of the study - Agree to refrain from receiving any elective dentistry (including dental prophylaxis) for the duration of the study - Agree to refrain from using any oral hygiene products other than the assigned study products for the duration of the study - Agree to comply with study/product usage instructions; and - Have at least one tooth with gingival recession and hypersensitivity evidenced by a score of ≥ 1 on the Cold Air Sensitivity Schiff scale during screening Exclusion Criteria: - Gross oral neglect or urgent dental treatment needs - Severe periodontal disease and/or generalized mobility - Active treatment for periodontitis - Any disease or condition that could be expected to interfere with examination procedures or safe completion of the study - Self-reported pregnancy or nursing

Nəticə

İlkin nəticə tədbirləri

1. Change From Baseline Air Challenge [30 days]

The Schiff Sensitivity Scale was assessed for each test tooth via an evaporative air challenge. The examiner recorded the Schiff Index score corresponding to the response to the air challenge. The Schiff Index Sensitivity scale is scored as follows- 0: tooth/subject did not respond to stimulus, 1: tooth/subject responds to stimulus, but does not request discontinuation of stimulus, 2: tooth/subject responds to stimulus and requests discontinuation or moves form stimulus, 3: tooth/subject responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. The higher the Schiff score, the more sensitive the tooth. The mean change from Baseline was calculated for this measure.

İkincili Nəticə Tədbirləri

1. Change From Baseline Visual Analog Scale [30 Days]

Visual Analog Scale (VAS) - subjects are asked to look at a VAS and designate the level of hypersensitivity they experienced as a result of the thermal and water challenges using a continuum scale of 0 = No tooth pain up to 100 = Worst tooth pain ever experienced.

Effectiveness of Two Water-Based Potassium Oxalate Desensitizers

Açar sözlər

oxalate

kalium

potassium oxalate

hypersensitivity