Respiratory Physiology in Children With Febrile Seizures.
Açar sözlər
Mücərrəd
Təsvir
The aim of the study is the continuous non-invasive monitoring of
- body temperature
- respiratory rate
- transcutaneous pCO2
- heart rate
- pulsoxymetric SaO2 (arterial oxygen saturation) during a febrile illness
- in children without febrile seizures and
- in children who had suffered a febrile seizure during the actual febrile illness.
Children will be recruited from the emergency units of the Charité University Hospital and a large Community Hospital, matched according to age, gender and the cause of their febrile illness and their data will enter final analysis if their body temperature rose at least once to or above 38.0 degree C and changed more than 1.0 degree C during the observational period.
Tarixlər
| Son Doğrulandı: | 06/30/2013 |
| İlk təqdim: | 07/19/2013 |
| Təxmini qeydiyyat təqdim edildi: | 07/22/2013 |
| İlk Göndərmə: | 07/23/2013 |
| Son Yeniləmə Göndərildi: | 07/22/2013 |
| Son Yeniləmə Göndərildi: | 07/23/2013 |
| Həqiqi Təhsilin Başlama Tarixi: | 06/30/2011 |
| Təxmini İlkin Tamamlanma Tarixi: | 06/30/2014 |
| Təxmini İşin Tamamlanma Tarixi: | 11/30/2014 |
Vəziyyət və ya xəstəlik
Faza
Qol Qrupları
| Qol | Müdaxilə / müalicə |
|---|---|
| Febrile illness WITH febrile seizure The cohort comprises children aged between 3 months and 5 years who had a febrile seizure during the actual febrile disease. | |
| Febrile illness WITHOUT febrile seizure The cohort comprises children aged between 3 months and 5 years with a febrile illness who had never a febrile seizure. |
Uyğunluq Kriteriyaları
| Təhsil üçün uyğun yaşlar | 3 Months Üçün 3 Months |
| Təhsilə Uyğun Cinslər | All |
| Nümunə götürmə metodu | Non-Probability Sample |
| Sağlam Könüllüləri qəbul edir | Bəli |
| Kriteriyalar | Inclusion Criteria: - Febrile illness with body temperature ≥38.0 degree C - 50% of study population: never had a febrile seizure - 50% of study population: simple or complex febrile seizure within one day of investigation - Change of body temperature of ≥1.0 degree C during the monitoring period - Provision of written informed consent by the parents or guardians of the child - Artefact-free simultaneous measurement of respiratory rate, pCO2 (transcutaneous probe), body temperature (rectal probe), and heart rate during change of body temperature of ≥1.0 degree C. Exclusion Criteria: - Past history of afebrile seizures - Past history of neonatal seizures - Retarded psychomotor development - Chronic respiratory disease - Cardiologic disease - Severe other organ disease - Permanent medication for chronic disorder - Therapeutic increase of inspiratory oxygen concentrations during the observational period |
Nəticə
İlkin nəticə tədbirləri
1. Change of transcutaneous pCO2 per change of body temperature [mmHg/degree C] [First or second night of febrile illness]
2. Change of respiratory rate per change of body temperature [1/sec * degree C] [First or second night of febrile illness]
3. Change of transcutaneous pCO2 per change of respiratory rate [mmHg * sec] [First or second night of febrile illness]
