Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 2002-Apr
[Congestive heart failure and paraoxonase].
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OBJECTIVE
To determine the changes of paraoxonase activity in patients with heart failure.
METHODS
The serum paraoxonase (PON) activity of the heart failure group and controls was measured with phenylacetate as the substrate.
RESULTS
The serum PON activity of the heart failure patients significantly decreased as compared with the controls; after the treatment, the PON activity of heart failure was largely elevated; and the PON activity of the patients with heart failure was negatively correlated with tumor necrosis factor-alpha.
CONCLUSIONS
The PON activity of patients with congestive heart failure significantly decreases.
