women will be given 17-OHPC 250 mg intra-muscular at admission and every 7 days thereafter in addition to other conservative measures of early-onset PE

No intervention will be given apart from the usual conservative measures of early-onset PE

Preeclampsia

17 Hydroxyprogesterone Capronate

Ahmed Abbas

Progesterone in Expectantly Managed Early-onset Preeclampsia

Efficacy of 17-Hydroxyprogesterone Caproate in Expectantly Managed Early-onset Preeclampsia: A Randomized Controlled Study

blood pressure measured by mercury sphygmomanometer

Ahmed Mohamed Abbas

principal investigator

Assiut University

Weekly 17 alpa hydroxyprogesterone caproate (17p) injections plus Omega 3 supplements, 4 capsules per day for up to 5 weeks. Each capsule contained 200 mg of docosahexaenoic acid (DHA) and 300 mg of eicosapentaenoic acid (EPA).

Weekly 17 alpa hydroxyprogesterone caproate (17p) injections plus placebo capsules, 4 capsules per day for up to 5 weeks

Preterm Birth

Participants receive a weekly progesterone injection (17 alpha hydroxyprogesterone caproate) up to 37 weeks gestation and take daily Omega-3 supplements.

17 alpha-Hydroxyprogesterone Caproate and Omega-3 supplement

Participants receive a weekly progesterone injection (17P) up to 37 weeks gestation and take daily placebo supplements

17 alpha-hydroxy progesterone caproate and Placebo supplement

University of Alabama - Birmingham

Northwestern University

Wayne State University

Columbia University

University of North Carolina - Chapel Hill

Wake Forest University School of Medicine

Case Western University

Ohio State University

Drexel University

University of Pittsburgh Magee Womens Hospital

Brown University

University of Utah Medical Center

Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies

A Randomized Trial of Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in Pregnancies at High Risk

Delivery before 37 weeks including any miscarriages occurring after randomization

The data will be shared after completion and publication of the main analyses in accordance with NIH policy. The contact to obtain datasets is mfmudatasets@bsc.gwu.edu.

17 alpha hydroxyprogesterone/i̇ltihab

Progesterone in Expectantly Managed Early-onset Preeclampsia

Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies

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