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Background: Grains of paradise (Aframomum melegueta) K. Schum is used to flavour foods and used as memory enhancer and anti-aging in traditional African medicine. This study examine the influence of ethanolic seed extract of Aframomum melegueta (AFM) on cognitive impairment induced by scopolamine in
The therapeutic abilities of Tetrapleura tetraptera and Aframomum citratum fruits used as spices are attributed to their bioactive molecules, including polyphenols. Sometimes used together and heated, they can undergo denaturation. The aim of the current study is to optimize the
African ethnomedicine is essentially based on the traditional use of vegetal extracts. Since these natural drugs have shown health giving properties, in the present study we increased further the scientific basis supporting these data. We investigated the effects, on murine B16F10 melanoma cells, of
The chemical compositions and antioxidant capacities of seven spices consumed in Southern Nigeria were determined. They were purchased from majors markets in the study area. Edible portions of the spices were ground into fine powder and their nutrient and phytochemical compositions determined using
This study investigated and compared the antioxidative, antidiabetic effects and possible active compounds present in various solvent extracts of fruit, leaf and stem of Aframomum melegueta (Rosc.) K. Schum. Samples were sequentially extracted using solvents of increasing polarity. They were
BACKGROUND
Aframomum species are widely used as a food supplement and remedy in folklore medicine for the management of several diseases. This study was designed to investigate the acetylcholinesterase inhibitory activity and antioxidant properties of phenolic-rich extracts from two Aframomum
Background and Objectives: Bacterial urinary tract infection (UTI) is the most common ailment affecting all age groups in males and females. The commercial antibiotics usage augments antibiotics resistance and creates higher recurrence rates of such communal infections. Hence, this study is
Aframomum melegueta Schum (Zingiberaceae) is a perennial herb widely cultivated for its valuable seeds in the tropical region of Africa. The present study evaluated the antioxidant effects of methanolic seed extract of A. melegueta. The antioxidant effects were evaluated using in vitro, 2,
Background:Aframomum danielli is used in ethno-medicine for the treatment of several ailments and as a traditional food spice. Methods: The hydro-distilled leaf, stem, seed, rhizome and pod volatile oils of A. danielli were subjected to gas chromatography-mass spectrometry (GC-MS) analysis. Free
Aframomum melegueta is a commonly used African spice. Through a hepatoprotective bioassay-guided isolation, the chloroform fraction of A.melegueta seeds yielded one new diarylheptanoid named 3-(S)-acetyl-1-(4'-hydroxy-3', 5'-di methoxyphenyl)-7-(3″,4″, 5″-trihydroxyphenyl)heptane (1), and two new
This present study investigates the effect of an aqueous seed extract of Aframomum melegueta, on leukocytes migration and on phenylhydrazine-treated rat red blood cells (RBC). The effect of Aframomum melegueta on the number of white blood cells (WBC), in inflammatory exudates, was assessed by
Alligator pepper [Aframomum melegueta Roscoe K. (Zingiberaceae)] seeds have been reportedly used in folkloric medicine in the management of hypercholesterolemia and hypertension with limited scientific basis for their action. This study was conducted to characterize the amino acids in Alligator
OBJECTIVE
[corrected] The signs of aging may originate from natural processes or from exposure to the sun, wind, or other environmental factors. To evaluate the anti-aging effects of potential agents researchers must first identify and be able to quantify epidermal markers that change with aging.
The ameliorative effect of aqueous extracts of Piper guineense and Aframomum longiscapum on radiation-induced hepatic damage was evaluated. Rats were treated with a single dose of 600 rads (6 Gy) y-radiation to induce hepatic damage. Aqueous extracts of Piper guineense and Aframomum longiscapum (200
BACKGROUND
Studying photoexposed and photoprotected skin biopsies from young and aged women, it has been found that a specific zone, composed of the basal layers of the epidermis, the dermal epidermal junction, and the superficial dermis, is major target of aging and reactive oxygen species. We