the intervention will consist of 3 phases: a one week run-in period, 24 weeks strict KD and 24 weeks Modified Atkins Diet.
Every day, 40 g of KetoCal, a nutritionally complete ready-to-drink liquid, is foreseen to ensure adequate amounts of vitamins and minerals and to ensure ketosis during the night (some patients drink some sips of the shake during the night). During this run-in period, patients will become familiar with their diet and, in particular, they will learn which foods are allowed and which are not.

During the run-in period, the dietician will discuss the diet and maintenance of an isocaloric diet with the patients. As such, the diet of the control group will not change from their normal dietary pattern, unless a patient is following an Atkins-like diet. In the latter case, the patient will be asked to change the diet to a normal Belgian diet.

Lymphedema

Ketogenic Dieting

Ketocal, a nutritionally complete ready-to-drink liquid, is foreseen to ensure adequate amounts of vitamins and minerals will be used. After 24 weeks a Modified Atkins diet will be started.

Ketogenic diet

Isocaloric diet

UZ Leuven

Ketogenic Diet: a Novel Metabolic Strategy to Treat Lymphedema Patients?

measured with QOL questionnaire, a scale from 0-10 on 16 items, how higher the score, how higher the QOL

measured with Lymph ICF (international classification of functioning, disability and Health), a scale from 0-10 on 29 items, total score ranged from 0-100, 0-4: indicate no problem; 5-24 a small problem; 26-49: moderate problem; 50-95: severe problem; 96-100: very severe problem

Universitaire Ziekenhuizen Leuven

After baseline assessment, patients will be randomized in one of the treatment groups.
Randomization is performed according to 'www.randomization.com'. This free generator randomizes each subject to a single treatment by using the method of randomly permuted blocks.
Assessments are performed by a person blinded to the treatment allocation groups.
Randomization will be stratified for baseline lymphedema volume (3-9.9%, 10.0-19.9% and ≥20%), affected limb (arm or leg) and gender (females or males). The staff members who perform the measurements are blinded for the allocation.

The staff members who perform the measurements are blinded for the allocation.

alcohol withdrawal delirium/ödəm

Ketogenic Diet: a Novel Metabolic Strategy to Treat Lymphedema Patients?

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