Receives twice daily 100mg nitrofurantoin for 5 days following catheter removal

Receives twice daily matching placebo for 5 days following catheter removal

Receives twice daily 100mg nitrofurantoin for 5 days following catheter removal
Nitrofurantoin 100 MG: Patients will receive nitrofurantoin 100mg twice daily by mouth for 5 days

Nitrofurantoin

Receives twice daily matching placebo for 5 days following catheter removal
Placebo Oral Tablet: Matching placebo

Placebo

Total

Sex/Gender, Customized

Race/Ethnicity, Customized

Body Mass Index (BMI), kg/m^2

Parity

POP-Q is a measure of the degree of Pelvic Organ Prolapse present. Stage 0 is essentially no prolapse or descent of pelvic organs; higher stages indicate progressively larger degrees of prolapse. Stage 4 is the highest stage, and indicated prolapse that is equal to or greater than the total vaginal length (in cm) minus 2 cm

POP-Q Stage

Menopausal Status

Postmenopausal Hormone Use

Current Smoking

History of Recurrent UTI

Diabetes Mellitus

Preoperative PVR Volume (mL)

Creatinine Clearance

Participants may have had more than one procedure listed

Type of Procedure

Operative Time (mins)

Estimated Blood Loss (mL)

Length of Hospital Stay (days)

Duration of Catheterization (days)

Number of participants with a urinary tract infection in the first 30 days following pelvic reconstructive surgery

Number of participants with an adverse event only related to study drug administration

Adverse Events

Compliance assessed by use of a medication diary during treatment period

Medication Compliance

Overall Study

Dina Bastawros, MD

Catheter-Associated Urinary Tract Infection

Patients will receive nitrofurantoin 100mg twice daily by mouth for 5 days

Nitrofurantoin 100 MG

Placebo Oral Tablet

Atrium Health

Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery

Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (NAUTICA): A Randomized Controlled Trial

bacteriuria/nikotin

Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery

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