A total of 45 adult patients undergoing FESS procedure for sinusitis with postoperative nasal packing. Written informed consent will be obtained from all patients before randomization. Patients will be assigned to chlorepheniramine maleate group (A)

A total of 45 adult patients undergoing FESS procedure for sinusitis with postoperative nasal packing. Written informed consent will be obtained from all patients before randomization. Patients will be assigned to placebo group (A)

Agitated; State, Acute Reaction to Stress

Participants of group A will receive only one ampoule of 45.5 mg/ 2mL chlorepheniramine maleate diluted in 8 ml isotonic saline intravenous (I.V) prior to induction of general anesthesia by 30 minutes

Preemptive chlorepheniramine maleate intravenous injection

participants in group (B) will receive 10 ml isotonic saline (placebo) by the same route as control.

ephedrine hydrochloride/hypersensitivity

Preemptive Chlorepheniramine Maleate Reducing Postoperative Agitation

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