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1. The alkaloid, allocryptopine, was isolated from the chloroform extract of Glaucium arabicum. 2. The effect of allocryptopine on urinary bladder and ileal smooth muscles was investigated in this study. 3. Allocryptopine, in concentrations from 1 x 10(-5) to 3 x 10(-3) M caused a
The variability of the contents of tropane and isoquinoline alkaloids, ashes, Na, K, Ca, Mg, Fe, Mn, Cu, Zn, Co, Mo, Cr, Al, Ba, V, Ni, Sr, Cd, Pb, J, and Ag was studied in individual plants of the industrial population of belladonna (Atropa belladonna L.) and yellow horned poppy (Glaucium flavum
Glaucium flavum Grantz, population Ghom, contains 1.24% dicentrine, 0.89% bulbocapnine, and 0.05% salutaridine in dry aerial parts and root of the flowering plant. These alkaloids were detected for the first time in the Glaucium genus.
Glaucium flavum collected in Sardinia was studied using a phytochemical approach in order to evaluate its alkaloid composition and obtain a comparison with the alkaloid contents of the same species in populations of other geographic proveniences. In fact, different chemoecotypes of G. flavum have
Glaucium flavum Grantz, population Isfahan, contained four major alkaloids: dicentrine (0.8%), bulbocapnine (0.42%), protopine (0.35%), and salutaridine (0.2%). G. flavum Grantz, population Kazerun, contained four major alkaloids: dicentrine (1.4%), bulbocapnine (0.5%), O-methylflavinantine (0.5%),
Glaucium oxylobum Boiss and Buhse, population Ab-Ali, was demonstrated to contain one major alkaloid, glaucine (0.7%), and two minor alkaloids, O-methylatheroline and predicentrine, in the aerial parts. The root also contains protopine. Glaucine and O-methylatheroline were detected for the first
BACKGROUND
Benzylisoquinoline alkaloids (BIAs) represent a diverse class of plant specialized metabolites sharing a common biosynthetic origin beginning with tyrosine. Many BIAs have potent pharmacological activities, and plants accumulating them boast long histories of use in traditional medicine
Glaucium vitellinum Boiss and Buhse. population Seerjan was shown to contain three major alkaloids, isocorydine (0.44%), protopine (0.42%), dicentrine (0.24%), and four minor alkaloids, tetrahydropalmatine (0.13%), muramine (0.12%), bulbocapnine (0.06%) and glaucine (0.01%). Glaucium pulchrum Stapf
Selected alkaloids are chromatographed on cyanopropyl-silica thin layers using various nonaqueous and aqueous eluents. Because of the strong retention of these basic compounds, nonaqueous eluents containing medium polar diluents, strongly polar modifiers, and silanol blockers (ammonia or
Retention parameters of alkaloid standards were determined on different stationary phases, i.e., octadecyl silica, base-deactivated octadecyl silica, cyanopropyl silica, preconditioned cyanopropyl silica, and pentafluorophenyl, using different aqueous eluant systems: acetonitrile-water mixtures;
Some standards of the alkaloids and synthetic or natural mixtures are separated by two-dimensional thin-layer chromatography (TLC) on different adsorbent layers. Normal- and reversed-phase systems are used to obtain significant differences in the separation selectivity. Optimization of the
Six isoquinoline alkaloids, glaucine, isocorydine, protopine, cryptopine, allocryptopine and trans-canadine methochloride, have been obtained from the aerial parts of Glaucium grandiflorum Boiss. et Huet var. torquatum Cullen, a plant indigenous to Turkey. The presence of a seventh alkaloid,
The alkaloid spectrum of the yellow horned poppy G. flavum was studied in early stages of development of this plant by methods of thin-layer chromatography and spectrophotometry. It was established that gradual formation of the alkaloid complex takes place in parallel with growth differentiation of
Glaucium flavum is used in Algerian folk medicine to remove warts (benign tumors). Its local appellations are Cheqiq el-asfar and Qarn el-djedyane. We have recently reported the anti-tumoral activity of Glaucium flavum root alkaloid extract against human cancer cells, in vitro and in vivo. The
Glaucine ((S)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo [de,g]quinoline) is an isoquinoline alkaloid and main component of Glaucium flavum (Papaveraceae). It was described to be consumed as recreational drug alone or in combination with other drugs. Besides this, glaucine is used