high-flow oxygen therapy administered during first night, ambient air without high-flow therapy (placebo) administered during second night

Ambient air without high-flow therapy (placebo) administered during first night , high-flow oxygen therapy administered during second night

Heart Failure，Congestive

Patients will receive oxygen with humidified air, fully saturated at 37° C at a flow rate of 20- 50 L/min. The ratio of oxygen and ambient air (FiO2) will be increased stepwise depending on patient's oxygen saturation.

Oxygen

Ambient air without high-flow therapy administered during first night

Placebo

Heart and Diabetes Center North-Rhine-Westphalia

High-Flow-Therapy for the Treatment of Cheyne-Stokes-Respiration in Chronic Heart Failure

Reduction of hypoxemic burden >50% compared to baseline using oxygen-HFT versus placebo

Thomas Bitter

Senior physician

Heart and Diabetes Center North-Rhine Westfalia

Obstructive Sleep Apnea

Acute Kidney Failure

Chronic Kidney Disease

After being qualified into the study according to the aforementioned inclusion criteria and after giving an informed consent the polysomnography will be performed in all patients during night rest.In all patients eligible to sleep apnea treatment according to apnea/hypopnea index (AHI, number of apneic/hypopneic episodes per 1 h of effective sleep) from diagnostic polysomnography, CPAP treatment will be introduced under polysomnographic surveillance and the same panel of clinical and biochemical parameters will be evaluated.

hypocapnia/infarction

High-Flow-Therapy for the Treatment of Cheyne-Stokes-Respiration in Chronic Heart Failure

Effect of Obstructive Sleep Apnea on Central Blood Pressure and Kidney and Endothelial Function

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