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In recent decades, there is increasing evidence suggesting that hyperoxia and hypocapnia are associated with poor outcomes in critically ill patients with cardiac arrest or traumatic brain injury. Yet, the impact of hyperoxia and hypocapnia on neurological outcome in patients with subarachnoid
In this editorial, the issues of hypocapnia and its relation to symptomatic vasospasm, prognosis, and outcome among patients with aneurysmal subarachnoid hemorrhage is discussed. Potential directions for future studies are provided.
BACKGROUND
Anesthetic management during functional endoscopic sinus surgery is aimed at minimizing bleeding and establishing a near-perfect surgical field. We investigated whether deliberate intraoperative hypercapnia and hypocapnia may affect blood loss and quality of surgical field through a
OBJECTIVE
To examine the relationship between PaCO2 levels in ventilated very preterm infants and (i) the incidence of severe intraventricular haemorrhage (IVH) and periventricular leukomalacia (PVL); and (ii) bronchopulmonary dysplasia (BPD).
METHODS
A retrospective cohort analysis of preterm
Background: An association between spontaneous hyperventilation, delayed cerebral ischemia, and poor clinical outcomes has been reported in subarachnoid hemorrhage. We evaluated the relationship between early pCO2 changes,
BACKGROUND
The impact of hypocapnia on outcome in aneurysmal subarachnoid hemorrhage (SAH) is unclear, although hypocapnia is associated with poor outcome in other brain injuries. We sought to determine the incidence and impact of hypocapnia in mechanically ventilated patients with aneurysmal
Ten splenectomized and ten nonsplenectomized conscious dogs were subjected to hemorrhage of 41% of their blood volume over a 15-minute period. Hemodynamic and metabolic variables were monitored for 4 hours after hemorrhage. Mortality (100%) occurred in the splenectomized group. Significant (P <
Positive pressure ventilation, using high inspiratory pressures, often causes lung damage. When associated with hypocapnia, it can produce severe focal alveolar alkalosis and can cause damage in areas of low blood flow. A vein-to-vein extracorporeal membrane oxygenator (ECMO) system was used to
Nicardipine, a calcium channel antagonist derivative of dihydropyridine, is a cerebral vasodilatator used in the treatment of cerebral vasospasms induced by subarachnoid hemorrhage after rupture of intracranial aneurysm. Hypocapnia is a powerful vasoconstrictor of cerebral arteries, and antagonizes
This study was undertaken to examine further the effects of hypocapnia and the contribution of hypotension to the haemodynamic consequences of cerebral arteriovenous fistula ablation in the rat chronic carotid-jugular fistula model. Regional cerebral blood flow (rCBF) was measured by the
BACKGROUND
Extended periods of
hypocarbia in preterm infants may be associated with intraventricular
hemorrhage, periventricular leukomalacia, and bronchopulmonary dysplasia. To evaluate the current anesthetic practice in preterm neonates, we retrospectively reviewed the
We evaluated the usefulness of monitoring jugular saturation (SjO2) in subarachnoid haemorrhage patients. SjO2 is an index of the global ratio between cerebral blood flow and metabolism. Low SjO2 identified global cerebral flow reduction, as due to low cerebral perfusion pressures or hypocapnia, but
The present study tests the hypothesis that changes in the strong inorganic ion concentrations contribute significantly to the acid-base disturbance that develops during hemorrhage in the arterial plasma of rats in addition to lactate concentration ([Lac-]) increase. The physicochemical origins for
UNASSIGNED
WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Hypocapnia, hypotension, and hypertension during aneurysm occlusion in patients with an aneurysmal subarachnoid hemorrhage may lead to a poor prognosis, but evidence for end-tidal carbon dioxide (ETCO2) and mean arterial pressure (MAP)