CTA abdominal and aortoiliac vasculature before transplantation
FeMRA abdominal and aortoiliac vasculature & CMR before transplantation

US vascular mapping before fistula creation
6 week US fistula arm
FeMRA fistula arm/central veins & CMR before fistula creation and at 6 weeks

US vascular mapping before graft creation
6 week US graft arm
FeMRA fistula arm/central veins & CMR before graft creation and at 6 weeks

Ferric Compounds

Magnetic Resonance Angiography

Vascular Grafting

Arteriovenous Fistula

Kidney Transplantation

NHS Greater Glasgow and Clyde

Ferumoxytol Enhanced Magnetic Resonance Angiography in Chronic Kidney Disease

Use of Ferumoxytol Enhanced Magnetic Resonance Angiography for Cardiovascular Assessment in Late-stage Chronic Kidney Disease

Multiple cross sections of various vascular beds obtained with currently used imaging techniques will be compared with matched sections obtained with FeMRA in a blinded fashion. The emphasis is generally on imaging quality and diagnostic accuracy on identification of clinically significant anatomic characteristics or lesions.

Outcomes include:
Sonographic anatomical fistula maturation at 6 weeks after creation.
Criteria of sonographic AVF maturation include:
AVF lumen diameter >4mm and
AVF blood flow >500mL/min
Fistula or graft complications: stenosis, thrombosis, hand ischaemia, aneurysm or pseudoaneurysm, infiltration, fistula bleeding, and infection.
Fistula or graft procedures: surgical revision, angioplasty, stent placement, thrombolysis or thrombectomy, ligation of accessory veins, superficialisation of vein, transposition of vein, central venous catheter use, and placement of new arteriovenous access.

nephrogenic fibrosing dermopathy/carbohydrate

Ferumoxytol Enhanced Magnetic Resonance Angiography in Chronic Kidney Disease

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