10 nəticələr
This invention concerns tricyclic pyridine N-oxides which act as vasopressin agonists, as well as methods of treatment and pharmaceutical compositions utilizing these compounds.
BACKGROUND OF THE INVENTION
Vasopressin (antidiuretic hormone, ADH) a nonapeptide hormone and neurotransmitter, is
This invention concerns novel tricyclic diazepines with affinity for the vasopressin and/or oxytocin receptors which can act as modulators of vasopressin and/or oxytocin effects in vivo, as well as methods of their manufacture, methods of treatment and pharmaceutical compositions utilizing these
This invention concerns tricyclic compounds, or pharmaceutical salts thereof, which act as vasopressin agonists, as well as methods of treatment and pharmaceutical compositions utilizing the compounds.
BACKGROUND OF THE INVENTION
Vasopressin (antidiuretic hormone, ADH) a non-peptide hormone and
BACKGROUND OF THE INVENTION
Vasopressin (antidiuretic hormone, ADH) a non-peptide hormone and neurotransmitter, is synthesized in the supraoptic nuclei of the hypothalamus of the brain and is transported through the supraoptico-hypophyseal tract to the posterior pituitary where it is stored. Upon
The present invention concerns novel compounds having vasopressin agonist activity, as well as methods of treatment and pharmaceutical compositions utilizing the same.
BACKGROUND OF THE INVENTION
Vasopressin (antidiuretic hormone, ADH), a nine amino acid peptide hormone and neurotransmitter, is
This invention concerns cyclohexylphenyls which act as vasopressin V.sub.2 agonists, as well as methods of treatment and pharmaceutical compositions utilizing these compounds.
BACKGROUND OF THE INVENTION
Vasopressin plays a vital role in the conservation of water by concentrating the urine in the
This invention concerns cyclohexylphenyls which act as vasopressin V.sub.2 agonists, as well as methods of treatment and pharmaceutical compositions utilizing these compounds.
BACKGROUND OF THE INVENTION
Vasopressin plays a vital role in the conservation of water by concentrating the urine in the
This invention concerns tricyclic arylthiophene compounds which act as vasopressin V.sub.2 agonists, as well as methods of treatment and pharmaceutical compositions utilizing these compounds.
BACKGROUND OF THE INVENTION
Vasopressin (antidiuretic hormone, ADH) a nonapeptide hormone and
This invention concerns tricyclic arylthiophene compunds which act as vasopressin V.sub.2 agonists, as well as methods of treatment and pharmaceutical compositions utilizing these compounds.
BACKGROUND OF THE INVENTION
Vasopressin (antidiuretic hormone, ADH) a nonapeptide hormone and
This invention concerns tricyclic benzoheterocyclic carboxyamides which act as vasopressin V.sub.2 agonists, as well as methods of treatment and pharmaceutical compositions utilizing these compounds.
BACKGROUND OF THE INVENTION
Vasopressin (antidiuretic hormone, ADH) a nonapeptide hormone and