12 nəticələr
The localization of alkaline phosphatase in a calcifying epithelial odontogenic tumor obtained from a 53-year-old man was examined cytochemically. The majority of enzyme activity was associated with the epithelial cell membranes of the tumor, and faint activity was found in the cell membranes facing
OBJECTIVE
To investigate the activities of bone resorption related cytokines at the capsule wall of the keratocystic odontogenic tumor (KCOT) by histochemical and immunohistochemical double staining for tartrate-resistant acid phosphatase staining (TRAP), receptor activator of nuclear factor-kappaB
Clear cell odontogenic tumor, a rare epithelial jaw lesion of putative odontogenic origin, histologically resembles clear cell adenocarcinomas. Ultrastructural and histochemical features are described and support a non-glandular derivation. The intraosseous neoplasm is characterized by ovoid nests
A calcifying epithelial odontogenic tumor, simultaneously located in the two jaws (maxilla and mandible) was examined by histochemical and electron microscopic methods. Squamous tumor cells without secretory polarity were different from those of common ameloblastoma. High activities of alkaline
Keratocystic odontogenic tumors (KCOTs) are jaw lesions that can be either sporadic or associated with nevoid basal cell carcinoma syndrome, which typically occurs as multiple, aggressive lesions that can lead to large areas of bone destruction and resorption and cause major impairment and even jaw
Bone resorption in the jaws is one of the most severe complications of keratocystic odontogenic tumors (KCOTs), and can be treated by either enucleation or marsupialization. However, the effects of marsupialization on bone regeneration adjacent to KCOTs, and the mechanisms involved, are still
The ameloblastic fibrosarcoma is a rare variety of neoplasm. Three new cases reported here occurred within preexistent benign odontogenic tumors (ameloblastic fibroma or fibro-odontoma). These large, osteolytic tumors, spreading to adjacent soft parts, recurred after surgical treatment in two cases.
Ameloblastoma is the most common benign odontogenic tumor in Japan. It is believed that it expands in the jaw bone through peritumoral activation of osteoclasts by receptor activator of nuclear factor kappa-B ligand (RANKL) released from the ameloblastoma, as in bone metastases of cancer cells.
The ameloblastoma is usually thought to be devoid of any odontogenic capacity. However, the histological, ultrastructural and histoenzymological study of 5 cases demonstrates the fairly high level of differentiation of some ameloblastic cells in such neoplasms. Furthermore, it suggests very early
OBJECTIVE
An odontoma, which shows proliferating odontogenic epithelium and mesenchymal tissue, is one of the most common odontogenic tumors encountered. These are commonly found in tooth-bearing regions, although the etiology remains unknown. There are no previous reports of an established line of
The myxoma of the jaws represent 8% of the odontogenic tumours in our series (324 cases). The 5 cases described here were studied by histoenzymological and electron microscopic methods. The first method demonstrated in the majority of tumoral cells a high level of activity of alkaline phosphatases
BACKGROUND
Human telomerase reverse transcriptase (hTERT) is catalytic subunit of human telomerase.
METHODS
We studied the immortalization of a series of human dental and periodontal cells by ectopic expression of hTERT and co-expression of hTERT with human papilloma virus 16 (HPV16) or simian virus