8 mg dexamethasone, single preoperative infusion

Complication, Postoperative

10 mg/kg methylprednisolone mixed in 100 ml NaCl (sodium chloride), infusion over 30 minutes, prior to surgery

Methylprednisolone

Dexamethasone mixed in 100 ml NaCl, infusion over 30 minutes, prior to surgery

Dexamethasone

Rigshospitalet

Preoperative High Dose Steroids for Liver Resection- Effect on Complications in the Immediate Postoperative Period

High Dose Steroids for Liver Resection - Effect on Complications and Endothelial Function in the Immediate Postoperative Phase - a Randomized, Doubleblind, Controlled Trial

Number of patients with any complication at any time, during stay in the PACU. Complications according to DASAIMS discharge criteria (modified Aldrete criteria)

Amount of endothelial markers (Syndecan-1, soluble thrombomodulin, SE-Selectin, vascular endothelial growth factor (VEGF) )

Number of patients with post-operative cognitive impairment, according to 3-minute diagnostic confusion assessment method (3D-CAM)

every 60 minutes, during stay in PACU. Numeric Rating Scale (NRS 0-10)

During admission, self reported. Numeric Rating Scale (NRS 0-10)

During admission, self reported. (Light, none, moderate, heavy nausea)

All analgesics other than standard medication, during admission. From Medical record.

All antiemetics other than standard medication, during admission. From Medical record.

impact on ALAT (alanin-aminotransferase) post surgery

impact on INR (International Normalized Ratio) post surgery

Kristin Julia Steinthorsdottir

Principal Investigator

Rigshospitalet, Denmark

Participants in the study will be pregnant women attending the obstetric ER for routine term followup. This evaluation is generally conducted at week 39-41 of pregnancy. The current study will focus on women attending a regular followup, not considered to be at high risk.

Pre - Delivery Pregnant Women

Chronic Pain

Pain During Delivery

Tel Aviv Sourasky Medical Ceter

Assessment of Central Pain in the Peripartum Period

Use of anagesics (i.e. PCA) during and after delivery will be documented and compared with results of evaluation performed before delivery regarding tenderness, symptoms of fibromyalgia etc/

Information will be collected regarding pain levels during delivery, regarding hemodynamic changes during delivery, regarding the mode of delivery as well as standard neonatal data (APGAR score etc)

orthostatic intolerance/qanaxma

Preoperative High Dose Steroids for Liver Resection- Effect on Complications in the Immediate Postoperative Period

Assessment of Central Pain in the Peripartum Period

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