6 nəticələr
Cell suspension cultures of TABERNAEMONTANA DIVARICATA were found to produce relatively large amounts of indole alkaloids. For their isolation an ion-pair DCCC method was used in combination with preparative TLC. The alkaloids were identified as tabernaemontanine, perivine, vobasine, voaphylline,
A suspension culture of TABERNAEMONTANA ELEGANS was characterized on growth, nutrient uptake (carbohydrate, nitrogen, and phosphate), and on accumulation of indole alkaloids. Besides tryptamine seven indole alkaloids were isolated and identified: vobasine, vobasinol, perivine, isositsirikine,
Seven indole alkaloids were isolated and identified from the leaves of Tabernaemontana dichotoma Roxb. The major alkaloids were: perivine, 19-epi-voacristine, 12-methoxy-voaphylline and vobasine. (-)apparicine, 19-epi-iboxygaine and isomethuenine occurred in minor amounts.
Stemmadenine, the major alkaloid from the seeds of Tabernaemontana dichotoma, showed hypotensive activity and weak muscle relaxant activity. Perivine, vobasine, coronaridine and dichomine, some of the alkaloids found in the leaves, fruits and bark of T. dichotoma, also showed hypotensive and muscle
The isolation and structure elucidation of the three new bisindole alkaloids, gabunamine, tabernamine, and 19,20-epoxyconoduramine, from Tabernaemontana johnstonii stem bark are described. The isolation of the seven known alkaloids, conodurine, conoduramine, gabunine, isovacangine, ibogamine,
Certain active antileukemic and cytotoxic fractions prepared from Tabernaemontana holstii roots were investigated, resulting in the isolation of the known indole alkaloids conoduramine, conodurine, coronaridine, gabunine, 19-oxocoronaridine, pericyclivine, perivine, and vobasine. Two new alkaloids