Right Ventricular Outflow Tract Absent

Congenital Heart Disease

Pulmonary Valve Disorders

In this prospective comparative research, all patients will be divided into two groups randomly with 100 patients in each group. One group will use the new-designed PTFE valved conduits and another one will implant the bovine jugular vein valved conduits.

new-designed PTFE valved conduits

Bovine jugular vein valved conduits

Children's Hospital of Fudan University

Shanghai Children's medical center

Shanghai zhongshan hospital

New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract

New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract: A Multi-centre Clinical Research

Detect pulmonary artery forward blood flow (FFV) and reverse blood flow (BFV) by MRI. PR Index=BFV/FFV × 100%.

atril arrhythmia and/or ventricular arrhythmia

pressure gradient across the valve detected by dopplor echocardiography

right ventricular end-diastolic volume index detected by MRI

Shanghai Zhongshan Hospital

Shanghai Children's Medical Center

Patients involved in this research should meet the requirement that they need valved conduits to reconstruct right ventricular outflow tract, first time operation and reoperation to change the decayed conduit included.

An 8-F long sheath will be inserted through the femoral vein and advanced to the main PA (MPA). The nMARQ Circular or Crescent (Biosense Webster) catheter will be advanced along this long sheath. After gently withdrawing the sheath and pushing the PADN catheter, the tip will be released from the sheath. Then, the tip of the catheter will be positioned first at the ostium of the left PA (Level 1 of ablation, <2 mm distal to orifice. After ablation at this level, the catheter tip will be positioned at the ostium of right PA (Level 2 of ablation, <2mm proximal to the bifurcation level). Finally, denervation of main pulmonary artery will be done by pulling the denervation catheter back into Level 3 of ablation (<2 mm proximal to both ostia of right and left PA-s) into main pulmonary artery.

Hypertension, Pulmonary

Radiofrequency denervation of right and left pulmonary arteries ostia and of main pulmonary artery <2 mm proximal from both ostia of right and left pulmonary arteries.

pulmonary valve insufficiency/heparin

New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract

Catheter Denervation of Pulmonary Arteries in Treatment of IPAH & SPAH

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