Səhifə 1 dan 75 nəticələr
BACKGROUND
Testicular damage caused by ischemia reperfusion injury can be determined by malondialdehyde (MDA) expression and grading of the histopathological damage to seminiferous tubules. The aim of this study was to investigate the effect of Tationil Glutathione administration on testicular
Testicular torsion is a serious problem in male children and, if not treated at the right time, can lead to subfertility and infertility. The main reason for testicular damage is ischemia-reperfusion injury. A number of chemical substances have been used to protect testes against
Despite the prompt diagnosis and treatment of testicular torsion (TT), there are problems with fertility and atrophy after testicular salvage. Dexpanthenol (Dxp) is the biologically active alcohol of pantothenic acid (PA). Dxp is converted to PA in tissues. PA increases the content of reduced
OBJECTIVE
This experimental study used a rat model to investigate the effect of a tunica albuginea incision with tunica vaginalis flap coverage on tissue damage and oxidative stress caused by testicular torsion and its relationship with the duration of ischemia.
METHODS
The test animals were divided
OBJECTIVE
To investigate the protective effect of astragalus on testis tissues following unilateral testicular torsion/detorsion.
METHODS
Thirty healthy adult Wistar rats were equally randomized into Group A (sham-operation control), B (torsion/detorsion) and C (torsion/detorsion plus
Testicular torsion/detorsion induces oxidative/nitrosative stress, inflammation and apoptosis of testicular tissues. Baicalin exerts antioxidant and anti-inflammatory properties. This study investigated the possible protective effect of baicalin against testicular torsion-detorsion injury in rats.
OBJECTIVE
To compare the efficacy of ozone with melatonin, shown as the most powerful antioxidant in attenuation of testicular ischemia/reperfusion injury, in an experimental rat model of testicular torsion/detorsion.
METHODS
Twenty-four male Wistar rats were divided into 4 groups: sham-operated,
OBJECTIVE
To compare the effects of intraepididymal quercetin (IE-QE) with those of intraperitoneal quercetin (IP-QE) on testicular torsion/detorsion (TD)-induced ischemia/reperfusion (IR) injury of the testes in an experimental rat model.
METHODS
Twenty-four rats were divided into 4 groups: sham
This study was done in order to determine the molecular and biochemical alterations following testicular torsion (TT) and torsion-reperfusion (TR). For this purpose, 54 male Wistar rats were divided into five groups as control group (n = 6) and experimental group subjected to 1, 2, 4, and 8 h
OBJECTIVE
To investigate the effect of ozone and/or taurine treatment comparatively on testicular damage due to ischemia/ reperfusion (I/R) injury in an experimental torsion model in rats.
METHODS
Adult Wistar rats with and without torsion/detorsion were used. In order to monitor the effect of ozone
The study was designed to evaluate the effects of metformin on apoptosis and epididymal sperm quality in a rat testicular ischaemia/reperfusion (I/R) injury model. A total of 72 male rats were divided into four groups (n = 18 for each group): group 1 (sham-operated group), group 2 (metformin group),
OBJECTIVE
To investigate the protective effect of zofenopril on torsion/detorsion-induced biochemical and histopathological changes in experimental testicular ischemia or reperfusion injury in rats.
METHODS
A total of 35 prepubertal male Wistar-Albino rats were divided into five groups, including 7
OBJECTIVE
We wanted to show early and late biochemical, histopathological, and apoptotic changes caused by unilateral spermatic cord torsion in ipsilateral and contralateral testicles and the effect of the poly (adenosine triphosphate-ribose) polymerase (PARP) inhibitor, nicotinamide, on these
Testicular torsion is a urological emergency both in childhood and in adult life. Many studies on experimental testicular torsion have demonstrated biochemical and pathological ischemia-reperfusion injury and the efficacy of some drugs have been investigated to prevent this damage. OBJECTIVE
Testicular torsion is a urological emergency. Failure of timely intervention for this issue leads the testicles to go into necrosis. If left untreated, it can lead to loss of the reproductive organs. The aim of this study was to examine the role of aliskiren in testicular torsion and