Transgender, Silicone and Blood Smear
Ключавыя словы
Рэферат
Апісанне
Injectable liquid silicone is a permanent filling product which is no more used in France because of a high risk of complications. Cosmetic silicone injection is a common feminization approach for transgender populations.
This cross-sectional monocentric study will describe transgender men transitioning into women and who had cosmetic silicone injection.
The principal objective is to estimate the prevalence of Transgender with circulating monocytes containing silicone vacuoles in blood smears among Male to Female Transgender population with a history of cosmetic silicon injections.
The secondary objectives are to describe the transgender population, to describe the quantity of silicone in vacuoles of circulating monocytes, and the association between dermatological complications (inflammatory and not inflammatory) and several clinical and biological characteristics (HIV status, level of immunosuppression, inflammatory syndrome, quantity of silicone which was injected , silicone quantity in blood smears).
Даты
| Апошняя праверка: | 08/31/2015 |
| Упершыню прадстаўлена: | 09/29/2015 |
| Меркаваная колькасць заявак прадстаўлена: | 10/17/2015 |
| Першае паведамленне: | 10/19/2015 |
| Апошняе абнаўленне адпраўлена: | 01/21/2016 |
| Апошняе абнаўленне апублікавана: | 01/24/2016 |
| Фактычная дата пачатку даследавання: | 06/30/2015 |
| Разліковая дата першаснага завяршэння: | 11/30/2015 |
| Разліковая дата завяршэння даследавання: | 12/31/2015 |
Стан альбо хвароба
Фаза
Групы ўзбраенняў
| Рука | Ўмяшанне / лячэнне |
|---|---|
| Cosmetic silicone injection People responding to inclusion criteria with a history of cosmetic silicone injection |
Крытэрыі прыдатнасці
| Узрост, які мае права на вучобу | 18 Years Каб 18 Years |
| Пол, прыдатны для навучання | Male |
| Метад адбору проб | Non-Probability Sample |
| Прымае здаровых валанцёраў | Так |
| Крытэрыі | Inclusion Criteria: - Adults - Not in opposition to data collection - Transgender men transitioning into women patients with cosmetic silicone injection - Consultation in Bichat hospital Exclusion Criteria: - Unable to communicate - Guardianship, curatorship |
Вынік
Першасныя вынікі
1. The prevalence of Transgender with circulating monocytes containing silicone vacuoles in blood smear among Male to Female Transgender population, the day of their consultation. [1 day ,the day of their consultation]
Меры другаснага выніку
1. Number of monocytes with vacuoles of silicone in a standardized area of 25 monocytes per blood smear slide [1 day ,the day of their consultation]
2. Size of silicone vacuoles in monocytes [1 day ,the day of their consultation]
3. Inflammatory and not inflammatory dermatological complications [1 day ,the day of their consultation]
4. Number of patients with a positive HIV status [1 day ,the day of their consultation]
5. Level of immunosuppression estimated with viral charge [1 day ,the day of their consultation]
6. Level of immunosuppression estimated with cluster of differentiation 4 cell (CD4) rate [1 day ,the day of their consultation]
7. Inflammatory syndrome estimated with C-reactive protein (CRP) [1 day ,the day of their consultation]
8. Inflammatory syndrome estimated with ferritin [1 day ,the day of their consultation]
9. Amount of injected silicone, in liters [1 day ,the day of their consultation]
10. Time since the first silicone injection for cosmetic purposes, in years [1 day ,the day of their consultation]
11. Comorbidities: Number of patients with history of Tuberculosis [1 day ,the day of their consultation]
12. Comorbidities: Number of patients with history of Hepatitis B [1 day ,the day of their consultation]
13. Comorbidities: Number of patients with history of Hepatitis C [1 day ,the day of their consultation]
14. Comorbidities: Number of patients with history of Syphilis [1 day ,the day of their consultation]
