Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Ключавыя словы
Рэферат
Даты
Апошняя праверка: | 07/31/2020 |
Упершыню прадстаўлена: | 06/13/2012 |
Меркаваная колькасць заявак прадстаўлена: | 11/14/2012 |
Першае паведамленне: | 11/20/2012 |
Апошняе абнаўленне адпраўлена: | 08/02/2020 |
Апошняе абнаўленне апублікавана: | 08/03/2020 |
Фактычная дата пачатку даследавання: | 06/30/2010 |
Разліковая дата першаснага завяршэння: | 11/30/2020 |
Разліковая дата завяршэння даследавання: | 11/30/2020 |
Стан альбо хвароба
Ўмяшанне / лячэнне
Radiation: [11-C]OMAR
Фаза
Групы ўзбраенняў
Рука | Ўмяшанне / лячэнне |
---|---|
Schizophrenia Patients diagnosed with schizophrenia both on medication and off medication | |
Cannabis dependence Frequent users of cannabis | |
Family history of alcoholism Healthy volunteers with a first degree relative with alcoholism | |
Prodrome for psychotic illness Not meeting full criteria for psychotic illness but exhibiting prodromal symptoms | |
Healthy Volunteers Healthy volunteers with no current or past major medical or psychiatric history | |
PTSD-Post Traumatic Stress Disorder Patients diagnosed with Post Traumatic Stress Disorder | |
Opioid Use Disorder Patients diagnosed with Opioid Use Disorder |
Крытэрыі прыдатнасці
Узрост, які мае права на вучобу | 18 Years Каб 18 Years |
Пол, прыдатны для навучання | Male |
Метад адбору проб | Probability Sample |
Прымае здаровых валанцёраў | Так |
Крытэрыі | Inclusion Criteria: - Males ages 18-55 - For cannabis users: - Willing to abstain from cannabis use for four weeks - For schizophrenia: - Meets DSM-IV-TR criteria for schizophrenia or schizoaffective disorder - For prodrome for psychotic illness: - Meets SIPS criteria for prodromal syndrome - For family history positive: - First degree relative with alcoholism - For Post-Traumatic Stress Disorder - Meets DSM-IV-TR criteria for PTSD - For OUD - Meets DSM-IV-TR criteria for Opioid Use Disorder Exclusion Criteria: - Current neuro-psychiatric illness (including cannabis dependence) or severe systemic disease. Cannabis use disorder is permitted in the cannabis dependent group. Schizophrenia and schizoaffective disorder is permitted in the schizophrenia group. Psychotic symptoms are permitted in the prodromal group. Post-Traumatic Stress Disorder is permitted in the PTSD group and Opioid Use Disorder is permitted in the OUD group. - Presence of ferromagnetic metal in the body or heart pacemaker - Have had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limits - Are claustrophobic |
Вынік
Першасныя вынікі
1. PET Imaging [One time within 4 weeks of screening]