Infectious Causes of Uveitis
Ключавыя словы
Рэферат
Апісанне
All patients included eye examination that includes split-lamp examination with semi-quantification evaluation of the inflammation, fundoscopy incl. picture, and angiography.
Hemoglobin (Hb), Erythrocyte-volume fraction (EVF), Middle cell volume (MCV), middelcell hemoglobin concentration (MCHC), Trombocyte
- Alanin-aminotransferase (ALAT), S-albumin, S-bilirubin (total), Protrombin complex, INR.
- Na, K, creatinin,
- CRP, Leukocyte and differential count
- ACE (Angiotensin Converting Enzyme)
- S-Ca2+
X-ray of thorax
The biopsies taken from the patient are in the routine program are patients tested for intraocular infections with Herpes Simplex Virus, Cytomegalovirus, Varicella Zoster virus, Epstein-Barr virus and toxoplasma with PCR and serology on serum. Test for others infections like Candida spp. and Toxocare are done if clini-cally indicated. Other test includes cytopathological test of the corpus vitreum for cancer cells and serological test for Syphilis.
Beside the above mentioned test will we in this study test for:
Infections with Leptospira, Bartonella, Brucella, Mycobacterium tuberculosis, Leptospira, Toxocare, Borrelia, HIV.
We will use unspecific molecular test for Bacteria under a special setup to avoid DNA contamination. Culture of Leptospira will be done on urine samples.
Даты
Апошняя праверка: | 04/30/2014 |
Упершыню прадстаўлена: | 05/07/2008 |
Меркаваная колькасць заявак прадстаўлена: | 05/11/2008 |
Першае паведамленне: | 05/12/2008 |
Апошняе абнаўленне адпраўлена: | 05/13/2014 |
Апошняе абнаўленне апублікавана: | 05/14/2014 |
Фактычная дата пачатку даследавання: | 03/31/2008 |
Разліковая дата першаснага завяршэння: | 08/31/2010 |
Разліковая дата завяршэння даследавання: | 08/31/2010 |
Стан альбо хвароба
Фаза
Групы ўзбраенняў
Рука | Ўмяшанне / лячэнне |
---|---|
Uveitis Patients suffering from uveitis, who have vitrectomy performed for diagnostic purpose | |
Control group Patients suffering from either "Epiretinal fibrosis" og "Macula hole" who have vitrectomy performed for curative reasons |
Крытэрыі прыдатнасці
Узрост, які мае права на вучобу | 18 Years Каб 18 Years |
Пол, прыдатны для навучання | All |
Метад адбору проб | Non-Probability Sample |
Прымае здаровых валанцёраў | Так |
Крытэрыі | Inclusion Criteria: - Patient at Glostrup Hospital refferal eye clinic with uveitis were vitrectomy will be performed for diagnostic reasons Exclusion Criteria: - patients where eye surgery has been performed on the affected eye, within 30 days before the current vitrectomy - Patients with known lymphoma - Patient with clinical suspicion of intra-ocular cancer disease - Pregnant and lactating women |
Вынік
Першасныя вынікі
1. Prevalence and distribution of intraocular infections in the study group [September 2010]
Меры другаснага выніку
1. The value of non-specific molecular diagnostic methods for detection of bacteria in the study group [September 2010]