To Study Polycystic Ovary Syndrome in Taiwanese Women
Ключавыя словы
Рэферат
Апісанне
1. Method
1. This study was approved by the Institutional Review Board of the Wan Fang Medical Center at Taipei Medical University (WF99041, approved August 2010) and performed at the Reproductive Endocrinology Clinic at the Wan Fang Medical Center from 31 August 2010 to 31 August 2011. The following women were excluded: (i) women who had been diagnosed with hyperprolactinemia, hypogonadotropic hypogonadism, premature ovarian failure, congenital adrenal hyperplasia, androgen-secreting tumor,Cushing's syndrome, disorders of the uterus and chromosomal anomalies; (ii) women who were less than three years past menarche or who were older than 45 years; (iii) women who received hormones or medication for major medical diseases (diabetes or cardiovascular disease); and (iv) women who had had ovarian cysts or ovarian tumors identified by ultrasonographic examination.
2. Statistical analysis: We used chi-squared and Fisher's exact tests to perform categorical comparisons and ANOVA to compare the continuous variables. The means of more than two groups were compared using one-way ANOVA and post hoc Dunnett's t-test with equal variances not assumed.
Даты
Апошняя праверка: | 11/30/2015 |
Упершыню прадстаўлена: | 12/06/2010 |
Меркаваная колькасць заявак прадстаўлена: | 12/07/2010 |
Першае паведамленне: | 12/08/2010 |
Апошняе абнаўленне адпраўлена: | 12/07/2015 |
Апошняе абнаўленне апублікавана: | 01/12/2016 |
Дата першых прадстаўленых вынікаў: | 11/27/2013 |
Дата першага прадстаўлення вынікаў кантролю якасці: | 12/07/2015 |
Дата вынікаў першага размяшчэння: | 01/12/2016 |
Фактычная дата пачатку даследавання: | 07/31/2010 |
Разліковая дата першаснага завяршэння: | 05/31/2013 |
Разліковая дата завяршэння даследавання: | 05/31/2013 |
Стан альбо хвароба
Фаза
Групы ўзбраенняў
Рука | Ўмяшанне / лячэнне |
---|---|
Control The normal reproductive-aged women | |
PCOS Women who met the 2003 Rotterdam criteria, which require a minimum of two of the following three criteria:
Oligo- or anovulation
Clinical and/or biochemical signs of hyperandrogenism
Polycystic ovaries and exclusion of other etiologies (congenital adrenal hyperplasia, androgen-secreting tumors, Cushing's syndrome) |
Крытэрыі прыдатнасці
Узрост, які мае права на вучобу | 15 Years Каб 15 Years |
Пол, прыдатны для навучання | Female |
Метад адбору проб | Probability Sample |
Прымае здаровых валанцёраў | Так |
Крытэрыі | Inclusion Criteria: - women at reproductive age - women with PCOS and women without PCOS. Exclusion Criteria: - young women who had their menarche less than 3 years - women older than 45 years old, Amenorrhea of menopause, hyperglycemia, hyperthyroidism, hypothyroidism, heart failure, lung failure, renal failure, anemia, dystrophy, gonitis. |
Вынік
Першасныя вынікі
1. Total Testosterone [1 year]
2. BMI [1 year]
3. Fasting Insulin [1 year]
4. Fasting Glucose [1 year]
5. Two Hour Glucose [1 year]
6. Homeostasis Model Assessment Insulin Resistance Index (HOMA-IR) [1 year]
7. Cholesterol [1 year]
8. Triglycerides [1 year]
9. HDL [1 year]
10. LDL [1 year]
11. Impaired Glucose Tolerance [1 years]