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alcoholism/атлусценне

Спасылка захоўваецца ў буферы абмену
Старонка 1 ад 46 вынікі

Use of the aminoalkylindole JWH-073-M4 and related compounds as neutral CB1 receptor antagonists for the treatment of alcoholism, drug abuse, obesity, and obesity-related diseases

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
BACKGROUND Cannabis sativa L., also known as marijuana, has been used for centuries for its psychoactive and medicinal properties [82]. The term cannabinoid was originally coined for any compound isolated from Cannabis [85]. However, today it refers to any compound that demonstrates similar

Salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
FIELD OF THE INVENTION The present invention relates to salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines, to a process for producing them, to their use for producing pharmaceutical compositions and to pharmaceutical compositions containing these compounds. BACKGROUND OF THE

Salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
FIELD OF THE INVENTION The present invention relates to salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines, to a process for producing them, to their use for producing pharmaceutical compositions and to pharmaceutical compositions containing these compounds. BACKGROUND OF THE

Imidazoline compounds

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
TECHNICAL FIELD The present invention is useful in medical fields. In more detail, novel imidazoline compounds of this invention are useful as neuropeptide Y receptor antagonists and as agents for the treatment of various kinds of cardiovascular disorders, central nervous system disorders, metabolic

Imidazonline compounds

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
This application is a 371 of PCT/JP01/01312 filed Feb. 22, 2001. TECHNICAL FIELD The present invention is useful in medical fields. In more detail, novel imidazoline compounds of this invention are useful as neuropeptide Y receptor antagonists and as agents for the treatment of various kinds of

Pyridone derivatives

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
This application is a U.S. national stage of International Application No. PCT/JP03/03115 filed Mar. 14, 2003. TECHNICAL FIELD The present invention is useful in medical fields. In more detail, novel pyridone derivatives of the present invention have an effect as neuropeptide Y receptor antagonists

Spiro compounds

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
This application is a U.S. national stage of International Application No. PCT/JP02/07922 filed Aug. 2, 2002. TECHNICAL FIELD The present invention is useful in medical fields. In more detail, spiro compounds of the present invention have an effect as neuropeptide Y receptor antagonists and are

Serotonin and norepinephrine reuptake inhibitors and uses thereof

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
BACKGROUND OF THE INVENTION The market for neuroscience and women's health drugs has been moving towards the use of dual serotonin and norepinephrine reuptake inhibitors (SNRI) for first line treatment of various indications, as evidenced by the recent development of SNRI's such as Venlafaxine and

Serotonin and norepinephrine reuptake inhibitor and uses thereof

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
BACKGROUND OF THE INVENTION The market for neuroscience and women's health drugs has been moving towards the use of dual serotonin and norepinephrine reuptake inhibitors (SNRI) for first line treatment of various indications, as evidenced by the recent development of SNRI's such as Venlafaxine and

Piperazinyl-propyl-pyrazole derivatives as dopamine D4 receptor antagonists, and pharmaceutical compositions containing the same

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
CROSS REFERENCE TO RELATED APPLICATION This application claims the priority of Korean Patent Application No. 10-2007-0022845, filed on Mar. 8, 2007 in the KIPO (Korean Intellectual Property Office), the disclosure of which are incorporated herein in their entirety by reference. Further, this

Piperazinyl-propyl-pyrazole derivatives as dopamine D4 receptor antagonists, and pharmaceutical compositions containing the same

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
TECHNICAL FIELD The present invention relates to a piperazinyl-propyl-pyrazole derivative, a method of its preparation and a pharmaceutically acceptable salt comprising the same. BACKGROUND ART Dopamine is a neurotransmitter essential for neuronal signal transduction in animal brains including

N-sulfamoyl-N'-benzopyranpiperidine compounds and uses thereof

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
BACKGROUND OF THE INVENTION The present invention relates to novel N-sulfamoyl-N'-benzopyranpiperidines and their physiologically acceptable acid addition salts, to pharmaceutical compositions comprising them, processes for their preparation, and their use for the treatment and/or inhibition of

Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
FIELD OF THE INVENTION This invention relates to antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans, to processes for preparing them, methods of using them and to pharmaceutical compositions containing them. BACKGROUND OF THE INVENTION Major depression is a serious health

Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
BACKGROUND OF THE INVENTION Major depression is a serious health problem affecting more than 5% of the population, with a life-time prevalence of 15-20%. Selective serotonin reuptake inhibitors have produced significant success in treating depression and related illnesses and have become among the

Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene

Перакладаць артыкулы могуць толькі зарэгістраваныя карыстальнікі
Увайсці / Зарэгістравацца
BACKGROUND OF THE INVENTION Major depression is a serious health problem affecting more than 5% of the population, with a life-time prevalence of 15-20%. Selective serotonin reuptake inhibitors have produced significant success in treating depression and related illnesses and have become among the
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