6 вынікі
FIELD OF INVENTION
This invention relates to treatment of age-related hearing loss and disorders. More specifically, the invention comprises compositions of a hormone and non-steroidal anti-inflammatory drug (NSAID) and use of the compositions in treating age-related hearing loss and
FIELD OF THE INVENTION
The present invention is directed to specific cytokine antagonists, including TNF antagonists and IL-1 antagonists, for the treatment of hearing loss, including sensorineural hearing loss and presbycusis. The invention also includes methods of administration for these
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a method and composition for preventing and/or reversing sensorineural hearing loss (SNHL) or toxin-induced hearing loss. More specifically, this invention relates to the use of agents which augment inner ear antioxidant
This application incorporates-by-reference nucleotide and/or amino acid sequences which are present in the file named "120701.sub.--2094.sub.--79459_A_PCT_US_SubstituteSequenceListing.txt" which is 1,171 kB in size, and which was created Jul. 1, 2012 and which is contained in the text file filed
This application incorporates-by-reference nucleotide and/or amino acid sequences which are present in the file named "130422.sub.--2094.sub.--79459 AZ_PCT_US_SubstituteSequenceListing_LC.txt" which is 1.14 megabytes in size, and which was created Apr. 17, 2013, and which is contained in the text
BACKGROUND OF THE INVENTION
Large conductance calcium activated channels are broadly expressed in neurons and muscle where they modulate cellular activity and function. Decades of research support an ongoing interest in modulating large conductance Ca.sup.2+ activated K.sup.+ (BK) channel function