Effects of Moderate Altitude Training on Metabolic Parameters in Voluntary Study Participants With Metabolic Syndrome
Ключови думи
Резюме
Описание
Participate can subjects aged 40-70 years with metabolic syndrome according to the definition of AHA/NHLBI and IDF 2009 after declaring orally and written consent and if they authorize to process personal and sanitary data. The study involve 80 subjects with metabolic syndrome. They will be recruited by general practitioner, elect from the principal investigator and invited to participate in the trial. The 80 participants will be randomized in two groups.
Group A, moderate altitude group, 1900 m, 40 participants Group B, low altitude group, 400m, 40 participants Group A will spend 2 weeks at an altitude of 1900m and participants absolve a training program (3h, 4x a week, total training time 24h, training intensity 55-65% of maximal heart rate).
Group B will spend spend 2 weeks at an altitude of 400m and participants absolve a training program (3h, 4x a week, total training time 24h, training intensity 55-65% of maximal heart rate).
Nutrition does not follow any specific diet plan, both groups receive an equivalent balanced feeding.
Clinical examinations at the beginning and at the end of the study laboratory tests well be documented and compared(fasting plasma glucose, triglycerides, HDL-C, LDL-C, insulin, C-peptid, free fatty acids, adiponectin, leptin, HbA1c, Metabolon cluster, c reactive protein, vit D3). Also BMI, BIA bioimpedance analysis, blood pressure, heart rate, egg, Physical status, exercise test.
Дати
| Последна проверка: | 03/31/2014 |
| Първо изпратено: | 11/05/2013 |
| Очаквано записване подадено: | 12/10/2013 |
| Първо публикувано: | 12/16/2013 |
| Изпратена последна актуализация: | 04/25/2014 |
| Последна актуализация публикувана: | 04/28/2014 |
| Действителна начална дата на проучването: | 10/31/2013 |
| Приблизителна дата на първично завършване: | 10/31/2013 |
| Очаквана дата на завършване на проучването: | 11/30/2014 |
Състояние или заболяване
Интервенция / лечение
Other: 2 weeks of exercise in low and moderate altitude
Фаза
Групи за ръце
| Arm | Интервенция / лечение |
|---|---|
| Other: Moderate altitude group 2 weeks of exercise at 1900 meters sea level | |
| Other: low altitude group 2 weeks of exercise at 400 meters sea level |
Критерии за допустимост
| Възрасти, отговарящи на условията за проучване | 30 Years Да се 30 Years |
| Полове, допустими за проучване | All |
| Приема здрави доброволци | Да |
| Критерии | Inclusion Criteria: waist circumference in men >102 cm, in women >88cm serum triglycerides >150 mg/dl or drug treatment serum HDL cholesterol < 40 mg/dl in men or <50 mg/dl in women or drug treatment blood pressure >130/95 or drug treatment fasting plasma glucose >100 mg/dl or drug treatment 3 from this 5 criteria - Exclusion Criteria: positive anamnesis for myocardial infarction,chronic heart disease, cerebral ischemic occurrences , mental and psychic disorders, not controlled hypertension or hyperglycemia, tumor desease, lung disorders,pregnancy - |
Резултат
Първични изходни мерки
1. exercise test [examination after 2 weeks of exercise]
Вторични изходни мерки
1. BMI, BIA, metabolic and cardiorespiratory parameters [examination on baseline and after the 2 weeks]
Други изходни мерки
1. blood pressure, heart rate [at baseline and after 2 weeks of exercise]
