Comparison of Complete Decongestive Therapy With Intermittent Pneumatic Compression for Treatment of Lipedema
Ключови думи
Резюме
Описание
Lipedema is a chronic, progressive and hereditary adipose tissue disorder characterized by an abnormal increase of subcutaneous adipose tissue, especially in the lower extremities. It is often seen in female sex. The main determinants of lipedema are bilateral symmetric swelling of the hypodermis of the legs which are painful with palpation or spontaneous and easy ecchymosis and hematoma with minor trauma.
Lipedema usually begins in the period of hormonal change in adolescence or after a few years and can progress in women during hormone changes such as pregnancy, gynecologic surgery or menopause.
Lipedema is a different diagnosis from obesity, but it can be misdiagnosed as primary obesity due to clinical overlap. In contrast to obesity, lipoedema may not improve with weight loss and does not include the risk of metabolic syndrome such as diabetes, hypertension and dyslipidemia. However, if not treated for lipedema, medical complications such as hypermobility, joint problems, walking difficulties, and psychological complications such as anxiety and depression may develop.
However, if not treated for lipedema, medical complications such as hypermobility, joint problems, walking difficulties and psychological complications such as anxiety and depression may develop.
Treatment for lipedema includes conservative and surgical options. In conservative treatment to control edema, combined decongestive treatment which consists of manual lymphatic drainage and compression bandaging, intermittent pneumatic compression and exercise options are included.
The aim of this study was to compare the effects of combined decongestive treatment and intermittent pneumatic compression treatment combined with aerobic exercise on pain, quality of life and fatigue in patients with lipedema.
Дати
| Последна проверка: | 12/31/2019 |
| Първо изпратено: | 04/21/2019 |
| Очаквано записване подадено: | 04/21/2019 |
| Първо публикувано: | 04/22/2019 |
| Изпратена последна актуализация: | 01/17/2020 |
| Последна актуализация публикувана: | 01/21/2020 |
| Действителна начална дата на проучването: | 04/21/2019 |
| Приблизителна дата на първично завършване: | 11/21/2019 |
| Очаквана дата на завършване на проучването: | 12/21/2019 |
Състояние или заболяване
Интервенция / лечение
Combination Product: Combined decongestive treatment & Combined exercise
Combination Product: Intermittent pneumatic compression & Combined exercise
Combination Product: Combined exercise
Фаза
Групи за ръце
| Arm | Интервенция / лечение |
|---|---|
| Experimental: Combined decongestive treatment & Combined exercise Combined decongestive treatment consists of manual lymphatic drainage and compression bandaging for 5 days a week, for 6 weeks (totally, 30 sessions).
All participants received 30 minutes aerobic exercise program including treadmill training consisted of a 5-minute warm-up and cool-down period and 25-minute submaximal aerobic exercise 5 days a week, for 6 weeks. Exercise intensity was calculated from the initial 6MWT. Each session was completed with 15 minutes of strengthening and stretching exercises. | Combination Product: Combined decongestive treatment & Combined exercise Combined decongestive treatment consists of manual lymphatic drainage and compression bandaging for 30 sessions. |
| Experimental: Intermittent pneumatic compression & Combined exercise Intermittent pneumatic compression for 5 days a week, for 6 weeks (totally, 30 sessions).
All participants received 30 minutes aerobic exercise program including treadmill training consisted of a 5-minute warm-up and cool-down period and 25-minute submaximal aerobic exercise 5 days a week, for 6 weeks. Exercise intensity was calculated from the initial 6MWT. Each session was completed with 15 minutes of strengthening and stretching exercises. | Combination Product: Intermittent pneumatic compression & Combined exercise Intermittent pneumatic compression for 5 days a week, for 6 weeks (totally, 30 sessions). |
| Active Comparator: Combined exercise All participants received 30 minutes aerobic exercise program including treadmill training consisted of a 5-minute warm-up and cool-down period and 25-minute submaximal aerobic exercise 5 days a week, for 6 weeks. Exercise intensity was calculated from the initial 6MWT. Each session was completed with 15 minutes of strengthening and stretching exercises. | Combination Product: Combined exercise 30 minutes aerobic exercise program including treadmill training consisted of a 5-minute warm-up and cool-down period and 25-minute submaximal aerobic exercise 5 days a week, for 6 weeks. Exercise intensity was calculated from the initial 6MWT. Each session was completed with 15 minutes of strengthening and stretching exercises. |
Критерии за допустимост
| Възрасти, отговарящи на условията за проучване | 18 Years Да се 18 Years |
| Полове, допустими за проучване | Female |
| Приема здрави доброволци | Да |
| Критерии | Inclusion Criteria: - Subject diagnosed with lipedema according to the criteria of revised Wold. - Subject did not participate in any exercise program within the last three months. - No pregnancy / breastfeeding Exclusion Criteria: - History of acute infection, cancer, inflammatory rheumatic / connective tissue diseases - History of cardiovascular or musculoskeletal problems that may prevent them from participating in the exercise program |
Резултат
Първични изходни мерки
1. Extremity volumetric measurement [6 weeks]
Вторични изходни мерки
1. Waist circumference [6 weeks]
2. Waist-to-hip ratio [6 weeks]
3. 6-minute walk test [6 weeks]
4. Visual analog scale for pain [6 weeks]
5. Short Form Health Survey 36 (SF-36) physical performance subscore SF-36 contains 36 items which are used to evaluate the quality of life of patients with chronic pain. [6 weeks]
6. Fatigue Severity Scale [6 weeks]
7. Beck Depression Inventory [6 weeks]
