Diet Selection Pre-Colonoscopy: Comparison Between Clear, Low-residue and Regular Diet
Ключови думи
Резюме
Описание
The study will be conducted in Makassed General Hospital (MGH) including all admitted patients receiving colonoscopy for the different indications. All patients will receive low volume 2L alpha peg split preps given 8 hours apart at a rate of 1 cup q 30 minutes with addition of 1 L of pure water post each liter with the addition 10mg of bisacodyl the night before.
In the trial, all adult inpatients (range, 18 to 80 years old) undergoing colonoscopy for CRC screening In MGH or with nonspecific gastrointestinal symptoms will be candidates for inclusion in the study. Exclusion criteria will be as follows: outpatient status; serious medical condi¬tions, such as severe cardiac, renal, liver, or metabolic disease; stroke or dementia; major psychiatric illness; known allergy to polyethylene glycol (PEG); a previous colon resection; incomplete colonoscopy examination (failure of cecal intubation); or functional constipation defined by Rome III diagnostic criteria.
Patient information was collected before procedure which included age, gender, weight, height, body mass index (BMI), indications for colonoscopy, and history of previous operation and colonoscopy, as well as bowel frequency. Patients will complete a questionnaire before colonoscopy regarding their preparation experience (the start and end time for PEG solution ingestion; the amount of PEG solution ingested; any associated adverse effects, includ¬ing abdominal pain, nausea, vomiting, headache, dizziness, and others; and willingness to repeat the same preparation in the future) with the help of an endoscopy nurse who will be blinded to the dietary randomization.
Participants were categorized into subgroups with regard to compliance; good compliance was defined as less than 25% of the PEG solution remaining, and poor compliance was defined as 25% or more of the PEG solution remaining. The subjects were randomly assigned to either eat Regular diet (RD), clear fluid diet (CLD) or low-residue diet (LRD) explained to each randomized case by in-hospital dietitian. In all three groups the offered diet was given at breakfast and lunch with fluids only given at dinner.
Дати
| Последна проверка: | 08/31/2019 |
| Първо изпратено: | 09/18/2018 |
| Очаквано записване подадено: | 09/20/2018 |
| Първо публикувано: | 09/23/2018 |
| Изпратена последна актуализация: | 09/25/2019 |
| Последна актуализация публикувана: | 09/26/2019 |
| Действителна начална дата на проучването: | 09/30/2018 |
| Приблизителна дата на първично завършване: | 05/29/2019 |
| Очаквана дата на завършване на проучването: | 05/29/2019 |
Състояние или заболяване
Интервенция / лечение
Other: Regular diet
Other: Clear fluid diet
Other: Low residue diet
Diagnostic Test: Colonoscopy
Фаза
Групи за ръце
| Arm | Интервенция / лечение |
|---|---|
| Experimental: Regular diet no dietary restriction | Other: Regular diet Patients will be provided with any type of food preferred at any time in any quantity |
| Placebo Comparator: Clear fluid diet no solid material | Other: Clear fluid diet Patients will be provided with
Plain water
Fruit juices without pulp, such as grape juice, filtered apple juice, and cranberry juice
Soup broth (bouillon or consommé)
Clear sodas, such as ginger ale and Sprite
Gelatin (Jell-O)
Tea or coffee with no cream or milk added
Sports drinks that don't have color |
| Experimental: Low residue diet easy digestible food | Other: Low residue diet The Low Residue Diet is the same as the soft diet with the added limitation of milk to one pint. It provides foods that are easily digestible. It is often used as a transition diet from liquids to the general diet. Indigestible fiber is reduced by using tender cooked vegetables and ripe, canned or cooked fruits from which the tough skins and seeds have been removed. Tender meat or meat made tender in the cooking process is used, thus reducing the amount of connective tissue.
Adequacy: By following the recommended guidelines, the diet will be adequate according to the Recommended Daily Allowance.
Note: For patients with dentures this diet can be modified by the substitution of ground meat for whole meat and excluding all raw vegetables. Personal tolerances determine food choices; avoid foods that cause GI (gastrointestinal) distress prior to the admission even though that food may be on the "foods included" list. |
Критерии за допустимост
| Възрасти, отговарящи на условията за проучване | 18 Years Да се 18 Years |
| Полове, допустими за проучване | All |
| Приема здрави доброволци | Да |
| Критерии | Inclusion Criteria: - inpatients 18 to 75 years old - undergoing colonoscopy for CRC screening - with nonspecific gastrointestinal symptoms Exclusion Criteria: - outpatient status; - serious medical conditions, such as severe cardiac, renal, liver, or metabolic disease; - stroke or dementia; - major psychiatric illness; - known allergy to PEG; - previous colon resection; - incomplete colonoscopy examination (failure of cecal intubation); - functional constipation defined by Rome III diagnostic criteria. |
Резултат
Първични изходни мерки
1. bowel preparation quality: Ottawa bowel preparation scale [within 15 minutes after procedure]
Вторични изходни мерки
1. best convenient dietary regimen [before procedure]
