Effect Of Intermittent Fasting To Metabolic And Oxidative Stress Marker
Ключови думи
Резюме
Описание
Intermittent fasting is eating pattern in that cycles between periods of fasting and eating. 5:2 intermittent fasting (IF) is a form of time-restricted fasting which no calories are consumed for at least 14 hours (for 4 am to 6 pm) will done in two non-consecutive days days per week, followed by ad libitum intake on the remaining days, with water restriction too.
Participants will be distributed to each group by simple randomization. This study will access the characteristic data, dietary intake and physical activity from the participants. Anthropometry and blood sample (for insulin resistance (HOMA-IR) and oxidative stress (malondialdehyde and catalase)) were taken at baseline and at the end of the study. Participants from each group will gets counseling at the second week of intervention and they will follow up to 8 weeks with control and evaluation form.
Дати
| Последна проверка: | 03/31/2020 |
| Първо изпратено: | 03/19/2020 |
| Очаквано записване подадено: | 03/22/2020 |
| Първо публикувано: | 03/23/2020 |
| Изпратена последна актуализация: | 04/07/2020 |
| Последна актуализация публикувана: | 04/09/2020 |
| Действителна начална дата на проучването: | 05/31/2020 |
| Приблизителна дата на първично завършване: | 07/31/2020 |
| Очаквана дата на завършване на проучването: | 08/31/2020 |
Състояние или заболяване
Интервенция / лечение
Behavioral: intervention
Фаза
Групи за ръце
| Arm | Интервенция / лечение |
|---|---|
| Experimental: intervention Participants will ask to do 5:2 intermittent fasting (2 non-consecutive days a week) within 8 weeks | Behavioral: intervention Doing fasting 2 days a week within 8 weeks |
| No Intervention: control Participants will not doing fasting or intake restriction within 8 weeks |
Критерии за допустимост
| Възрасти, отговарящи на условията за проучване | 30 Years Да се 30 Years |
| Полове, допустими за проучване | Male |
| Приема здрави доброволци | Да |
| Критерии | Inclusion Criteria: - Men aged 30-59 years - Has a BMI ≥ 25 kg/m^2 - Has a waist circumference of ≥ 90 cm - Willingness to participate in the whole study by signing informed consent Exclusion Criteria: - Doing regular fasting (2 days a week) for 12 weeks before the study begins. - In a certain diet at the moment - Participants who are taking drugs that can affect blood sugar, insulin, and drugs (steroids, beta blockers, adrenergics), vitamins or herbal supplements and other drugs that affect oxidative stress. - Participants suffering from obesity with complications such as impaired liver function, impaired kidney function, heart disease and type 2 diabetes mellitus are known through anamnesis and physical examination as well as fasting blood sugar checks. - Participants that has a fever with temperatures> 37.5 ℃ |
Резултат
Първични изходни мерки
1. insulin resistance [8 weeks]
2. catalase level [8 weeks]
3. plasma malondialdehyde level [8 weeks]
4. waist circumference [8 weeks]
Вторични изходни мерки
1. mean caloric intake [8 weeks]
