Gut Microbiome and Obesity
Ключови думи
Резюме
Дати
| Последна проверка: | 06/30/2020 |
| Първо изпратено: | 06/24/2020 |
| Очаквано записване подадено: | 06/24/2020 |
| Първо публикувано: | 06/29/2020 |
| Изпратена последна актуализация: | 06/30/2020 |
| Последна актуализация публикувана: | 07/06/2020 |
| Действителна начална дата на проучването: | 04/30/2020 |
| Приблизителна дата на първично завършване: | 04/30/2022 |
| Очаквана дата на завършване на проучването: | 04/30/2022 |
Състояние или заболяване
Интервенция / лечение
Other: Obese with or without metabolic syndromesubjects
Фаза
Групи за ръце
| Arm | Интервенция / лечение |
|---|---|
| Obese subjects Subjects with obesity | |
| Obese plus metabolic syndrome subjects Subjects with obesity and metabolic syndrome | |
| Healthy controls Otherwise healthy subjects |
Критерии за допустимост
| Възрасти, отговарящи на условията за проучване | 10 Years Да се 10 Years |
| Полове, допустими за проучване | All |
| Метод за вземане на проби | Probability Sample |
| Приема здрави доброволци | Не |
| Критерии | Inclusion Criteria: - Subjects aged between 10-16 years, - diagnosis of obesity or obesity complicated by metabolic syndrome - healthy controls Exclusion Criteria: - Age at enrollment < 10 or >16 years, - concomitant presence of chronic diseases, - neoplasms, - immunodeficiencies, - chronic infections, - autoimmune diseases, - chronic inflammatory bowel diseases, - celiac disease, -genetic-metabolic diseases, - - cystic fibrosis - chronic lung diseases, - malformations of the cardiovascular/respiratory/gastrointestinal system, - neuropsychiatric disorders - neurological pathologies, - assumption of antibiotics and/or pre/pro/synbiotics - onset of diarrhea or acute gastrointestinal disease during the 12 weeks prior to enrollment. |
Резултат
Първични изходни мерки
1. Concentration of metagenomic characteristics of the intestinal microbiota in subjects with obesity, obesity complicated by metabolic syndrome and healthy controls [at enrollment]
Вторични изходни мерки
1. Concentration of metabolomic characteristics of the intestinal microbiota in subjects with obesity, obesity complicated by metabolic syndrome and healthy controls [at enrollment]
2. Concentration of the metabolomic characteristics of the intestinal microbiota in subjects with obesity, obesity complicated by metabolic syndrome and healthy controls [at enrollment]
3. Concentration of the metabolomic characteristics of the intestinal microbiota in subjects with obesity, obesity complicated by metabolic syndrome and healthy controls [at enrollment]
4. Concentration of the metabolomic characteristics of the intestinal microbiota in subjects with obesity, obesity complicated by metabolic syndrome and healthy controls [at enrollment]
