Investigation of Oxidative Markers and Antioxidant Defense in Female Patients With Osteoarthritis
Ключови думи
Резюме
Описание
A total of 300 patients with osteoarthritis will be included in the study. The objective of the study is to investigate the eating behaviour of the patients included in the study by using a semiquantitative questionnaire (frequency and quantity) by estimating the foods that are known to be protective for osteoarthritis (vegetables, fruits, cereals) as the ones that are considered risk factors (meat origin, refined fats). Also, the weight and height of each patient will be assessed and the patients will be included in 4 classes based on the body mass index: underweight, normal weight, overweight and obese. The type of physical activity will also be noted and the oxidative-antioxidative balance will be evaluated by determining serum markers: oxidated glutathione/reducted glutathione, catalase enzyme, superoxide dismutase, glutathion peroxidase and malonyldialdehyde. Correlation between eating behaviour, body mass index and oxidative stress markers will be made.
Дати
| Последна проверка: | 11/30/2019 |
| Първо изпратено: | 12/17/2019 |
| Очаквано записване подадено: | 12/17/2019 |
| Първо публикувано: | 12/19/2019 |
| Изпратена последна актуализация: | 12/19/2019 |
| Последна актуализация публикувана: | 12/23/2019 |
| Действителна начална дата на проучването: | 07/16/2019 |
| Приблизителна дата на първично завършване: | 05/31/2020 |
| Очаквана дата на завършване на проучването: | 05/31/2020 |
Състояние или заболяване
Интервенция / лечение
Other: Osteoarthritis
Фаза
Групи за ръце
| Arm | Интервенция / лечение |
|---|---|
| Osteoarthritis Questionnaire of eating habits, markers of oxidative stress | Other: Osteoarthritis frequency and type of aliments |
Критерии за допустимост
| Полове, допустими за проучване | Female |
| Метод за вземане на проби | Probability Sample |
| Приема здрави доброволци | Да |
| Критерии | Inclusion Criteria: - osteoarthritis - signed informed consent Exclusion Criteria: - drugs or foods with antioxidant effects - lack of judgement - refuse to participate |
Резултат
Първични изходни мерки
1. serum concentration of oxidative stress markers [baseline]
