[Use of contrykal in intensive care of myocardial infarct during the prehospital stage].

The effect of contrykal was evaluated in 146 male patients with first myocardial infarction and 116 control patients in the prehospital period. Intravenous contrykal was given in a single dose of 20,000 IU within 30 to 360 minutes of onset of myocardial infarction, followed by intravenous administration of heparin, 10,000-15,000 U. The control patients received conventional therapy. Earlier application of contrykal contributed to attenuation of clinical manifestations of myocardial infarction. The drug was found to produce a clear-cut antianginal effect. It also exerted a positive action on the abdominal syndrome. There was a rapid inverse dynamics in ECG changes, fermentaemia (aspartate aminotransferase and alanine aminotransferase), decreased myocardial necrotic mass.