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candidiasis invasive/затлъстяване
Линкът е запазен в клипборда
5 резултата
Fractal geometry and the pharmacometrics of micafungin in overweight, obese, and extremely obese people.
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Вход / Регистрация
The majority of Americans are overweight, and the incidence of obesity continues to increase. This trend predisposes people to a number of deleterious consequences, including the metabolic syndrome and other conditions that lead to a greater number of hospital admissions. Invasive candidiasis is an
Efficacy and safety of caspofungin in obese patients.
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Вход / Регистрация
Safety and efficacy outcomes were retrospectively compared for obese versus non-obese patients who received standard caspofungin doses for different clinical conditions in nine clinical trials within the Merck caspofungin database. Favorable outcomes were as defined in specific protocols. Safety was
Dosing of antifungal agents in obese people.
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Вход / Регистрация
Obesity is a worldwide epidemic associated with multiple comorbidities that increase the risk of hospitalization. Very little pharmacokinetic data are available for antifungal agents in obesity, as this population is often excluded from drug development studies and these agents are less commonly
Impact of pharmacodynamics and pharmacokinetics on echinocandin dosing strategies.
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OBJECTIVE
Studies of antibiotic pharmacokinetics and pharmacokinetic-pharmacodynamics are useful in the design of optimal dosing strategies. This review examines recent advances in echinocandin pharmacokinetics and pharmacodynamics, and discusses how these studies could lead to newer dosing
Pharmacokinetic evaluation of fluconazole in critically ill patients.
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BACKGROUND
Invasive candidiasis has emerged over the last few decades as an increasingly important nosocomial problem for the critically ill, affecting around 2% of intensive care unit patients. Although poor outcomes associated with invasive candidiasis among critically ill patients may relate to
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