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Anti-inflammatory activity of rhein in animal models with potential mechanism of actions.Methods
Rhein was isolated from
Cassia fistula L. flowers collected in Chennai, Tamil Nadu, India. Its
anti-inflammatory activity was then investigated in
BACKGROUND
Cassia sophera Linn (Family Caesalpiniaceae), popularly known as kasundi, is used both in the Indian traditional system and folk medicine to treat several inflammatory pathologies such as asthma, arthritis and pains. The aim of the present study was to evaluate the scientific basis of
BACKGROUND
Nonsteroidal and steroidal drugs are generally used as a part of drug therapy in inflammation. However, these drugs have severe side-effects like nausea and vomiting. Therefore, there is a need to identify anti-inflammatory compounds that will be effective with a better safety profile.
OBJECTIVE
The present study was carried out to investigate analgesic and anti-inflammatory activities of Cassia siamea Lam stem bark extracts. We have also determined the cytotoxicity of each extract.
METHODS
C. siamea, a widespread medicinal plant traditionally used in sub-Saharan Africa, was
Natural products are used as alternative drugs in traditional medicine to treat infection and inflammation and relieve pain. Heartwood of Cassia garettiana Craib has been investigated as an ingredient in Thai traditional medicine for anti-HIV protease, but there is no report on its
Ononitol monohydrate (OM) was isolated from Cassia tora L. leaves. The anti-inflammatory and analgesic activities of OM have been examined in male Wistar rats and mice. The efficacy of OM against inflammation was studied by using carrageenan-induced paw oedema, croton oil-induced ear oedema, acetic
Cassiaindoline is a new dimeric indole alkaloid isolated from Cassia alata L. leaves whose structure was elucidated through spectroscopic analyses. It exhibited analgesic activity at a dosage of 125.0 mg/kg mouse and decreased the number of writhings induced by acetic acid by 49.4%. It also showed a
Antiinflammatory activities of heat-treated Cassia alata leaf extract and kaempferol 3-O-gentiobioside (K3G) isolated from C. alata as an abundant flavonoid glycoside were studied by comparing their activities with the activities of sun-dried C. alata leaf extract. We observed strong inhibitory
Cassia occidentalis Linn. mast cell degranulation at a dose of 250 mg/kg, showed dose dependent stabilizing activity towards human RBC, with is widely used in traditional medicine of India to treat a number of clinical conditions including allergy and inflammatory manifestations. In the present
Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was
OBJECTIVE
To investigate the anti-inflammatory effects of a hexane extract of Cassia alata leaves in complete Freund's adjuvant (CFA) arthritis in rats.
METHODS
A hexane extract of Cassia alata leaves was administered by oral gavage to CFA arthritic rats (500 mg/kg, n = 6). Controls received corn
Cassia oil (CO) from different parts of Cinnamomum cassia have different active components. Very few pharmacological properties of cassia leaf oil have been reported. This study investigated and compared effects of cassia leaf oil and cinnamaldehyde on lipopolysaccharide (LPS)-activated J774A.1
Chronic inflammation is a contributing factor in many age-related diseases. In a previous study, we have shown that Sri Lankan cinnamon (C. zeylanicum) was one of the most potent anti-inflammatory foods out of 115 foods tested. However, knowledge about the exact nature of the anti-inflammatory
We have investigated the anti-inflammatory effects of Cinnamomum cassia constituents (cinnamic aldehyde, cinnamic alcohol, cinnamic acid, and coumarin) using lipopolysaccharide (LPS)-stimulated mouse macrophage (RAW264.7) and carrageenan (Carr)-induced mouse paw edema model. When RAW264.7
BACKGROUND
Cinnamomum cassia Blume (Aceraceae) has been traditionally used to treat various inflammatory diseases such as gastritis. However, the anti-inflammatory mechanism of Cinnamomum cassia has not been fully elucidated. This study examined the anti-inflammatory mechanism of 95% ethanol extract