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phosphatase/инсулт

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6 резултата

Inhibitors of phosphatase and tensin homolog (PTEN) conjugates

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TECHNICAL FIELD This invention relates to therapeutics, their uses and methods for the treatment of various indications associated with cytotoxic or excitotoxic stress. In particular, peptides and compositions thereof, having phosphatase and tensin homolog (PTEN) inhibitory activity for use in and

Inhibitors of phosphatase and tensin homolog (PTEN) compositions, uses and methods

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TECHNICAL FIELD This invention relates to therapeutics, their uses and methods for the treatment of various indications associated with cytotoxic or excitotoxic stress. In particular, peptides and compositions thereof, having phosphatase and tensin homolog (PTEN) inhibitory activity for use in and

Immunophilin-binding agents prevent glutamate neurotoxicity associated with vascular stroke and neurodegenerative diseases

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FIELD OF THE INVENTION The invention relates to the use of inhibitors of calcineurin to prevent glutamate neurotoxicity. BACKGROUND OF THE INVENTION Nitric oxide (NO) has been demonstrated to mediate neuronal relaxation of intestines (Bult (1990) Nature, 345:346-347; Gillespie (1989) Br. J.

STEP-derived peptide for brain injury treatment

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SEQUENCE LISTING A sequence listing is submitted with the present application. The sequence listing is submitted as a .txt file entitled 7120107_SEQ_ST25.txt and is 12 kb in size. The entire contents of the sequence listing are hereby incorporated by reference. BACKGROUND Brain injury resulting from

STEP-derived peptide for brain injury treatment

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SEQUENCE LISTING A sequence listing is submitted with the present application. The sequence listing is submitted as a .txt file entitled 7120102_SEQ_ST25.txt and is 12 kb in size. The entire contents of the sequence listing are hereby incorporated by reference. BACKGROUND Brain injury resulting from

STEP-derived peptide for brain injury treatment

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SEQUENCE LISTING A sequence listing is submitted with the present application. The sequence listing is submitted as a .txt file entitled 7120107_SEQ_ST25.txt and is 12 kb in size. The entire contents of the sequence listing are hereby incorporated by reference. BACKGROUND Brain injury resulting from
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