Pyrazine / затлъстяване

Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors

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Вход / Регистрация

2. BACKGROUND Provided herein are certain heteroaryl compounds, compositions comprising an effective amount of one or more such compounds and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by

Pyrazine compounds as phosphodiesterase 10 inhibitors

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Вход / Регистрация

FIELD OF THE INVENTION Provided herein are certain pyrazine compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10,

Pyrazine compounds as phosphodiesterase 10 inhibitors

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Вход / Регистрация

FIELD OF THE INVENTION Provided herein are certain pyrazine compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10,

Pyrazine compounds as phosphodiesterase 10 inhibitors

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Вход / Регистрация

FIELD OF THE INVENTION Provided herein are certain pyrazine compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10,

Pyridine, pyrimidine and pyrazine derivatives as GPCR agonists

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Вход / Регистрация

BACKGROUND OF THE INVENTION The present invention is directed to G-protein coupled receptor (GPCR) agonists. In particular, the present invention is directed to agonists of GPR116 that are useful for the treatment of obesity, e.g. as regulators of satiety, and for the treatment of diabetes. Obesity

Substituted pyrazines as DGAT-1 inhibitors

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Вход / Регистрация

The present invention relates to compounds which inhibit acetyl CoA(acetyl coenzyme A):diacylglycerol acyltransferase (DGAT1) activity, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, methods for the treatment of disease states associated with

Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors

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Вход / Регистрация

2. BACKGROUND Provided herein are certain heteroaryl compounds, compositions comprising an effective amount of one or more such compounds and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by

Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors

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Вход / Регистрация

2. BACKGROUND Provided herein are certain heteroaryl compounds, compositions comprising an effective amount of one or more such compounds and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by

Halogen substituted pyrazines as intermediates of mTOR kinase inhibitors

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Вход / Регистрация

2. BACKGROUND Provided herein are certain heteroaryl compounds, compositions comprising an effective amount of one or more such compounds and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by

Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway

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Вход / Регистрация

2. BACKGROUND Provided herein are certain heteroaryl compounds, compositions comprising an effective amount of one or more such compounds and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by

Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/AKT pathway

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Вход / Регистрация

2. BACKGROUND Provided herein are certain heteroaryl compounds, compositions comprising an effective amount of one or more such compounds and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by

Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway

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Вход / Регистрация

BACKGROUND Provided herein are certain heteroaryl compounds, compositions comprising an effective amount of one or more such compounds and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by

[1,2,4] triazol [1,5-a] pyrazines useful as inhibitors of phosphodiesterases

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Вход / Регистрация

I. CROSS-REFERENCE TO RELATED APPLICATION This application claims priority to U.S. Provisional Patent Application No. 61/431,769, filed Jan. 11, 2011, the content of which is hereby incorporated by reference herein in its entirety. II. FIELD Provided herein are heteroaryl compounds useful for

Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

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Вход / Регистрация

FIELD OF THE INVENTION The present invention relates to novel compounds, to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of the compounds for the preparation of a medicament which particularly acts on the central nervous

Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

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Вход / Регистрация

FIELD OF THE INVENTION The present invention relates to novel compounds, to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of the compounds for the preparation of a medicament which particularly acts on the central nervous

pyrazine/затлъстяване

Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors

Pyrazine compounds as phosphodiesterase 10 inhibitors

Pyrazine compounds as phosphodiesterase 10 inhibitors

Pyrazine compounds as phosphodiesterase 10 inhibitors

Pyridine, pyrimidine and pyrazine derivatives as GPCR agonists

Substituted pyrazines as DGAT-1 inhibitors

Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors

Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors

Halogen substituted pyrazines as intermediates of mTOR kinase inhibitors

Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway

Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/AKT pathway

Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway

[1,2,4] triazol [1,5-a] pyrazines useful as inhibitors of phosphodiesterases

Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

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