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9 резултата
Pyrazine in prevention and treatment of strokes
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TECHNICAL FIELD
The field concerns the use of drugs, particularly tetraalkylpyrazines to reduce ischemic defects and/or improve survival associated with stroke.
BACKGROUND
Stroke is associated with the blockage of blood flow to one or more sites of the brain. If the period of blockage is long
Pyrazine derivatives and pharmaceutical use thereof
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TECHNICAL FIELD
The present invention relates to a novel pyrazine derivative and a salt thereof, which are useful as medicaments.
BACKGROUND ART
Adenosine is a ubiquitous biochemical messenger. Adenosine binds to and activates seven-transmembrane spanning G-protein coupled receptors, eliciting a
Pyrazine derivatives and pharmaceutical use thereof
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Вход / Регистрация
TECHNICAL FIELD
The present invention relates to a novel pyrazine derivative and a salt thereof, which are useful as medicaments.
BACKGROUND ART
Adenosine is a ubiquitous biochemical messenger. Adenosine binds to and activates seven-transmembrane spanning G-protein coupled receptors, eliciting a
Substituted 3,4-dihydropyrrolo[1,2-A]pyrazines as beta-secretase (BACE) inhibitors
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is the national stage of PCT Application No. PCT/EP2012/053863 filed Mar. 7, 2012, which claims priority from European Patent Application No. 11157418.2, filed Mar. 9, 2011, the entire disclosures of which are hereby incorporated in their
4-amino-6-phenyl-5,6-dihydroimidazo[1,5-A]pyrazine derivatives as inhibitors of beta-secretase (BACE)
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This application is the national stage of PCT Application No. PCT/EP2014/062285, filed Jun. 12, 2014, which claims priority from European Patent Application No. 13171730.8, filed Jun. 12, 2013, the entire disclosures of which are hereby incorporated in their
4-amino-6-phenyl-6,7-dihydro[1,2,3]triazolo[1,5-A]pyrazine derivatives as inhibitors of beta-secretase (BACE)
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is the national stage of PCT Application No. PCT/EP2014/062286, filed Jun. 12, 2014, which claims priority from European Patent Application No. 13171720.9, filed Jun. 12, 2013, the entire disclosures of which are hereby incorporated in their
Pyrido[4,3-B]pyrazine-2-carboxamides as neurogenic agents for the treatment of neurodegenerative disorders
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FIELD OF THE INVENTION
The present invention relates to novel compounds of formula I, wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are as described herein, having pharmaceutical activity, their manufacture, pharmaceutical compositions containing them and their potential use as
Certain 6, 8-(heteroaryl or aryl) disubstituted imidazo[1,2-a]pyrazines as modulators of Hsp90 complex activity
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FIELD OF THE INVENTION
This invention relates to certain imidazo[1,2-a]pyrazin-8-ylamines and related compounds, which when appropriately substituted are modulators of Hsp90 complex activity. Certain compounds provided herein are highly active inhibitors of Hsp90 complex activity. This invention
Lighting device having at least one heat sink
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a nationalization under 35 U.S.C. .sctn.371 of International Application No. PCT/CN2011/076756, filed on Jul. 1, 2011 and published as WO 2012/003784 A1, on Jan. 12, 2012, which claims priority under 35 U.S.C. .sctn.119 to Chinese
Най-пълната база данни за лечебни билки, подкрепена от науката
- Работи на 55 езика
- Билкови лекове, подкрепени от науката
- Разпознаване на билки по изображение
- Интерактивна GPS карта - маркирайте билките на място (очаквайте скоро)
- Прочетете научни публикации, свързани с вашето търсене
- Търсете лечебни билки по техните ефекти
- Организирайте вашите интереси и бъдете в крак с научните статии, клиничните изследвания и патентите
Въведете симптом или болест и прочетете за билките, които биха могли да помогнат, напишете билка и вижте болестите и симптомите, срещу които се използва.
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