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10 резултата
Derivatives of 3-hydroxyazabenzo(beta)thiophene useful as 5-lipoxygenase inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
Derivatives of 3-hydroxyazabenzo[b]thiophene useful as 5-lipoxygenase inhibitors
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
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Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly, 3-hydroxybenzo[b]thiophene-2-carboxamides, which are found to be effective cyclooxygenase and 5-lipoxygenase inhibitors and are therefore useful in the treatment of inflammation and other prostaglandin and
3-hydroxybenzo[b]thiophene-2-sulfide derivatives compositions, and method of use therefor
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Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 3-hydroxybenzothiophenes having the 2-sulfide side chains, for example, ##STR1##
These novel benzothiophenes are found to be effective and specific 5-lipoxygenase inhibitors and are therefore useful in the treatment
Anti-inflammatory and analgesic 3-hydroxybenzo[b]thiophene derivatives, compositions, and method of use therefor
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Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 3-hydroxybenzothiophenes, having the 2-carbon side chains, for example, 3-acetoxy-2-butyl-5-chloro-benzo[b]thiophene and its 2-benzyl analog.
These novel benzothiophenes are found to be either specific 5-lipoxygenase
N-alkenyl-2-hydroxybenzo(b)thiophene-3-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 2-hydroxybenzothiophenes having the unusual 3-enamido side chains, for example, ##STR1##
These novel compounds can be effective cyclooxygenase and 5-lipoxygenase inhibitors and therefore can be useful in the
N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 3-hydroxybenzothiophenes having the unusual 2-enamido side chains, for example, ##STR1##
These novel benzothiophenes are found to be effective cyclooxygenase and 5-lipoxygenase inhibitors and are therefore useful in
N-alkenyl-3-hydroxybenzo[b]thiophene-2-carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to benzothiophenes, particularly 3-hydroxybenzothiophenes having the unusual 2-enamido side chains, such as those of Formula I: ##STR2##
Compounds of formula I have been found to be effective inhibitors of both cyclooxygenase and lipoxygenase and
N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors
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Вход / Регистрация
BACKGROUND OF THE INVENTION
This invention relates to fused heterocyclic carboxamides, for example, N-(2,2-diphenylethenyl)-3-hydroxythieno[3,2-b]thiophene-2-carboxamide.
These novel compounds are found to be effective cyclooxygenase and 5-lipoxygenase inhibitors and are therefore useful in the
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