Tart Cherry Juice and Chronic Disease Risk
কীওয়ার্ডস
বিমূর্ত
বর্ণনা
In this study, the investigators recruited at-risk individuals (n=10) who were overweight (25.0-29.9 kg/m2) and obese (> 30.0 kg/m2) and likely to exhibit one or more conditions associated with MetS. Participants were >18 years of age, not pregnant, not diabetic, with no unresolved infections or diseases (diabetes, CVD, IBD, cancer and liver disease), and nonsmokers. Histories of medication and dietary supplement use were collected and those taking anti-inflammatory or lipid-lowering medications were excluded. After enrollment, subjects were randomly assigned to consume daily either 240 mL (8 ounces) of authentic TCJ (R.W. Knudsen, Chico, CA) or a placebo beverage (commercial fruit punch; Great Value, Bentonville, AR) for 4 weeks. After a 2-week washout period, participants consumed the alternate beverage for 4 weeks in this 10-week 2x2 crossover, placebo-controlled dietary intervention. Subsequently, the investigators determined the effect of TCJ in at-risk participants on markers of lipidemia (HDL, LDL, triglycerides, VLDL, total cholesterol), glycemia (fasting insulin and glucose, HOMA, QUICKI, McAuley indirect indices), and inflammation (hsCRP, TNF-alpha, and ESR).
তারিখ
| সর্বশেষ যাচাই করা হয়েছে: | 07/31/2018 |
| প্রথম জমা দেওয়া: | 08/15/2018 |
| আনুমানিক তালিকাভুক্তি জমা দেওয়া হয়েছে: | 08/15/2018 |
| প্রথম পোস্ট: | 08/19/2018 |
| সর্বশেষ আপডেট জমা দেওয়া হয়েছে: | 08/15/2018 |
| সর্বশেষ আপডেট পোস্ট: | 08/19/2018 |
| আসল অধ্যয়ন শুরুর তারিখ: | 08/20/2009 |
| আনুমানিক প্রাথমিক সমাপ্তির তারিখ: | 09/29/2011 |
| আনুমানিক অধ্যয়ন সমাপ্তির তারিখ: | 09/29/2011 |
অবস্থা বা রোগ
হস্তক্ষেপ / চিকিত্সা
Dietary Supplement: Placebo
Dietary Supplement: Tart cherry juice (TCJ)
পর্যায়
বাহু গ্রুপ
| বাহু | হস্তক্ষেপ / চিকিত্সা |
|---|---|
| Placebo Comparator: Placebo Participants randomized to consume either placebo beverage or tart cherry juice at beginning of the study followed by a 2 week washout then switch over to the alternate beverage. Approximately half of participants began study consuming placebo beverage and the other half TCJ. | Dietary Supplement: Placebo Participants consumed placebo beverage for 4 weeks. |
| Experimental: Tart cherry juice (TCJ) Participants randomized to consume either placebo beverage or tart cherry juice at beginning of the study followed by a 2 week washout then switch over to the alternate beverage. Approximately half pf participants began study consuming placebo beverage and the other half TCJ. | Dietary Supplement: Tart cherry juice (TCJ) Participants consumed tart cherry juice (8 ounces; 240 mL) per day for four weeks. |
যোগ্যতার মানদণ্ড
| বয়স অধ্যয়নের জন্য যোগ্য | 18 Years প্রতি 18 Years |
| লিঙ্গ অধ্যয়নের জন্য যোগ্য | All |
| স্বাস্থ্যকর স্বেচ্ছাসেবীদের গ্রহণ করে | হ্যাঁ |
| নির্ণায়ক | Inclusion Criteria: - This study was a 12-week 2 x 2 crossover, randomized, placebo-controlled dietary intervention in overweight and obese participants (BMI>25.0 kg/m2) who are more likely to exhibit >1 of the 5 risk conditions associated with metabolic syndrome (MetS). BMI was the minimal criterion for recruitment. Exclusion Criteria: - Participants were >18 years of age, not pregnant, not diabetic, with no unresolved infections or diseases (diabetes, CVD, IBD, cancer and liver disease), and nonsmokers. Histories of medication and dietary supplement use were collected and those taking anti-inflammatory or lipid-lowering medications were excluded. |
ফলাফল
প্রাথমিক ফলাফল ব্যবস্থা
1. TCJ and hsCRP [4 weeks]
মাধ্যমিক ফলাফলের ব্যবস্থা
1. fasting triglycerides [4 weeks]
