Cholera-Hospital-Based-Intervention-for-7-days

কেবল নিবন্ধিত ব্যবহারকারীরা নিবন্ধগুলি অনুবাদ করতে পারবেন

প্রবেশ করুন - নিবন্ধন করুন

লিঙ্কটি ক্লিপবোর্ডে সংরক্ষিত হয়েছে

স্থিতিসক্রিয়, নিয়োগ নয়

স্পনসর

Johns Hopkins Bloomberg School of Public Health

সহযোগী

International Centre for Diarrhoeal Disease Research, Bangladesh

ক্লিনিকাল ট্রায়াল: NCT04008134

BioSeek: nct04008134

কীওয়ার্ডস

বিমূর্ত

The Cholera Hospital Based Intervention for 7 Days (CHoBI7) randomized controlled trial for transition to scale aimed to: (1) Develop and evaluate scalable approaches to integrate the CHoBI7 intervention into the services provided for hospitalized diarrhea patients at health facilities in Bangladesh; and (2) Evaluate the ability of the CHoBI7 intervention to lead to a sustained uptake of the promoted hand washing with soap and water treatment behaviors and significant reductions in diarrheal disease over time.

বর্ণনা

The findings from the recent randomized controlled trial of The Cholera Hospital Based Intervention for 7 Days (CHoBI7) demonstrated that this intervention was effective in significantly reducing symptomatic cholera infections in intervention households, and had significant sustained impacts on hand washing with soap behaviors and improved water quality 12 months post intervention. Next steps to transition to scale were: (1) Develop and evaluate scalable approaches to integrate the CHoBI7 intervention into the services provided for hospitalized diarrhea patients at health facilities in Bangladesh; and (2) Evaluate the ability of the CHoBI7 intervention to lead to a sustained uptake of the promoted hand washing with soap and water treatment behaviors and significant reductions in diarrheal disease over time.

তারিখ

সর্বশেষ যাচাই করা হয়েছে:	07/31/2019
প্রথম জমা দেওয়া:	07/01/2019
আনুমানিক তালিকাভুক্তি জমা দেওয়া হয়েছে:	07/01/2019
প্রথম পোস্ট:	07/04/2019
সর্বশেষ আপডেট জমা দেওয়া হয়েছে:	08/19/2019
সর্বশেষ আপডেট পোস্ট:	08/21/2019
আসল অধ্যয়ন শুরুর তারিখ:	12/03/2016
আনুমানিক প্রাথমিক সমাপ্তির তারিখ:	04/29/2020
আনুমানিক অধ্যয়ন সমাপ্তির তারিখ:	04/29/2020

অবস্থা বা রোগ

Cholera

Diarrhea

হস্তক্ষেপ / চিকিত্সা

Behavioral: CHoBI7 health facility program

Behavioral: CHoBI7 mHealth program

Behavioral: mHealth with home visits

পর্যায়

বাহু গ্রুপ

বাহু	হস্তক্ষেপ / চিকিত্সা
No Intervention: Standard recommendation (ORS) Participants received the standard recommendation on oral rehydration solution use
Experimental: mHealth with no home visits Participants received the health facility delivery of CHoBI7, plus bi-weekly mHealth (voice and text) reminders for 12 months
Experimental: mHealth with home visits Participants received the health facility delivery of CHoBI7, plus two home visits and bi-weekly mHealth (voice and text) reminders for 12 months	Behavioral: mHealth with home visits The CHoBI7 home visit program involves two, 30-minute home visits conducted during the week after the index diarrhea patient was recruited at the health facility. A health worker reinforces the content of the CHoBI7 health facility program in the participant's home.

যোগ্যতার মানদণ্ড

লিঙ্গ অধ্যয়নের জন্য যোগ্য

All

স্বাস্থ্যকর স্বেচ্ছাসেবীদের গ্রহণ করে

হ্যাঁ

নির্ণায়ক

Inclusion Criteria:

Diarrhea patients will be defined as patients having acute watery diarrhea three or more loose stools over a 24-hour period in the past three days. Diarrhea patients admitted to ICDDRB Dhaka Hospital or Mugda General Hospital will be eligible for the trial if:

1. have had 3 or more loose stools over the past 24 hours

2. plan to reside in Dhaka for the next 12 months

3. have no basin for running water in their home

4. have a child under five years of age in their household (including themselves) that produced a stool sample at baseline

5. have a working mobile phone in the household.

Household members of the diarrhea patient will be eligible for the trial if:

1. they have shared the same cooking pot and resided in the same home with the diarrhea patient for the last three days

2. plan to reside in their current household with the diarrhea patient for the next 12 months

Exclusion Criteria:

(1) Children in foster care will be excluded from all research study activities.

ফলাফল

প্রাথমিক ফলাফল ব্যবস্থা

1. Diarrhea prevalence among children under 2 years of age [12 months]

Diarrhea prevalence among children under 2 years of age assessed by caregiver self report over a 12-month period

2. Diarrhea prevalence among children under 5 years of age [12 months]

Diarrhea prevalence among children under 5 years of age assessed by caregiver self report over a 12-month period

3. Diarrhea prevalence among all household members [12 months]

Diarrhea prevalence among all household members assessed by self report over a 12-month period

মাধ্যমিক ফলাফলের ব্যবস্থা

1. Diarrhea prevalence among participants ages 5-9 years [12 months]

Diarrhea prevalence among all household members ages 5-9 years assessed by self report over a 12-month period

2. Diarrhea prevalence among participants ages 10-18 years [12 months]

Diarrhea prevalence among all household members ages 10-18 years assessed by self report over a 12-month period

3. Diarrhea prevalence among participants ages greater than 18 years [12 months]

Diarrhea prevalence among all household members ages greater than 18 years assessed by self report over a 12-month period

4. Handwashing with soap [12 months]

Household members handwashing with soap at food and stool related events assessed by 5-hour structured observation over a 12-month period

5. Household drinking water treatment [12 months]

Households with stored drinking water samples without detectable E.coli (<1 colony forming units / 100 ml) assessed by unannounced household visits for sample collection of household stored drinking water over a 12-month period

6. Height-for-age among children under 2 years of age [12 months]

Height, weight and age measurements among children under 2 years of age assessed over a 12-month period were used to calculate height-for-age z-scores according to the World Health Organization child growth standards

7. Height-for-age among children under 5 years of age [12 months]

Height, weight and age measurements among children under 5 years of age assessed over a 12-month period were used to calculate height-for-age z-scores according to the World Health Organization child growth standards

8. Weight-for-age among children under 2 years of age [12 months]

Height, weight and age measurements among children under 2 years of age assessed over a 12-month period were used to calculate weight-for-age z-scores according to the World Health Organization child growth standards

9. Weight-for-age among children under 5 years of age [12 months]

Height, weight and age measurements among children under 5 years of age assessed over a 12-month period were used to calculate weight-for-age z-scores according to the World Health Organization child growth standards

10. Weight-for-height among children under 2 years of age [12 months]

Height, weight and age measurements among children under 2 years of age assessed over a 12-month period were used to calculate weight-for-height z-scores according to the World Health Organization child growth standards

11. Weight-for-height among children under 5 years of age [12 months]

Height, weight and age measurements among children under 5 years of age assessed over a 12-month period were used to calculate weight-for-height z-scores according to the World Health Organization child growth standards