Impact of Nutritional Intervention in Indian Female Cancer Cachexia Patients
কীওয়ার্ডস
বিমূর্ত
বর্ণনা
Patients were randomly distributed into two groups i.e. control and intervention group. 30 patients were allocated in intervention group and received nutrient rich bread mix i.e. IAtta (100 g) along with dietary and physical activity counseling and 33 patients were allocated in the control group who received only dietary and physical activity counseling. Patients in the intervention group collected 14 packets of 100 g of IAtta every fortnight during their clinician appointments while the control patients were advised regarding their dietary habits at every clinician visit for 6 months.
Dietary counseling for 30 minutes was imparted to all patients on each visit by the researcher. Depending on the physical status of the patients, low level of physical activity (walking and/or stairs), was encouraged daily during counseling sessions.
Nutritional, biochemical, quality of life and anthropometric estimations were assessed at baseline, after 3 months and at 6 months of intervention for all patients.
Patients' daily energy, carbohydrate, protein and fat intake were calculated using food frequency (Indian Migrant study food frequency questionnaire- IMS-FFQ) questionnaire and two day 24 hour recall data. PG-SGA questionnaire was used to monitor patient nutritional status throughout the study.
EORTC-QLQ- C30 questionnaire was used to analyse patients' quality of life and asked personally by the researcher.
Haemoglobin and serum albumin levels were assessed at the start of the study, after 3 months and at 6 months of intervention for all patients.
Indian Migrant Study Physical Activity questionnaire (IMS-PAQ) was used to assess patients' physical activity throughout the day.
Anthropometric estimations included body weight, mid upper arm circumference and four site skin fold thickness (SFT) measurement (i.e. triceps, biceps, subscapular and suprailiac).
তারিখ
| সর্বশেষ যাচাই করা হয়েছে: | 12/31/2014 |
| প্রথম জমা দেওয়া: | 01/25/2015 |
| আনুমানিক তালিকাভুক্তি জমা দেওয়া হয়েছে: | 01/28/2015 |
| প্রথম পোস্ট: | 01/29/2015 |
| সর্বশেষ আপডেট জমা দেওয়া হয়েছে: | 01/28/2015 |
| সর্বশেষ আপডেট পোস্ট: | 01/29/2015 |
| আসল অধ্যয়ন শুরুর তারিখ: | 11/30/2013 |
| আনুমানিক প্রাথমিক সমাপ্তির তারিখ: | 06/30/2014 |
| আনুমানিক অধ্যয়ন সমাপ্তির তারিখ: | 07/31/2014 |
অবস্থা বা রোগ
হস্তক্ষেপ / চিকিত্সা
Dietary Supplement: Intervention group
Other: Nutritional counseling
Behavioral: Physical activity counseling
পর্যায়
বাহু গ্রুপ
| বাহু | হস্তক্ষেপ / চিকিত্সা |
|---|---|
| Experimental: Intervention group Patients in the intervention group were given dietary supplement (Improved Atta: 100 g) daily along with nutritional counseling and physical activity counseling for six months. | Dietary Supplement: Intervention group Improved Atta is a multi macro- micronutrient bread mix. Patients were given 100 grams of Improved Atta (in the from of unleavened bread) everyday for consumption for six months. |
| Other: Control group Patients in the control group were given nutritional and physical activity counseling for six months every fortnight. |
যোগ্যতার মানদণ্ড
| বয়স অধ্যয়নের জন্য যোগ্য | 18 Years প্রতি 18 Years |
| লিঙ্গ অধ্যয়নের জন্য যোগ্য | Female |
| স্বাস্থ্যকর স্বেচ্ছাসেবীদের গ্রহণ করে | হ্যাঁ |
| নির্ণায়ক | Inclusion Criteria: - Female, age 18 years and above. - Diagnosed with cancer. - Weight loss >5% from pre-treatment weight or BMI<20kg/m2. - Hemoglobin level <12 g/dl. - Energy intake < 1500 kcal/d (to be assessed on consultation). Exclusion Criteria: - Incapable to provide written consent. - Patient diagnosed with refractory cachexia. - Life expectancy < 3 months. - Unresponsive to anti-cancer therapy. - Patient is a pregnant woman or a nursing mother. - Suffering from secondary illnesses. - Gastrointestinal tract defects which affect nutrient absorption |
ফলাফল
প্রাথমিক ফলাফল ব্যবস্থা
1. Body weight [6 months]
মাধ্যমিক ফলাফলের ব্যবস্থা
1. Mid upper arm circumference (MUAC) [6 months]
2. Body fat percentage (BF%) [6 months]
3. Nutritional status assessment (Indian Migrant study food frequency questionnaire (IMS-FFQ), two day 24 hour dietary recall and patient generated subjective global assessment) [6 months]
4. Physical activity assessment (Indian Migrant Study Physical Activity questionnaire (IMS-PAQ) [6 months]
5. Quality of life (QoL) assessment (EORTC-QLQ- C30 questionnaire) [6 months]
6. Haemoglobin (Haemoglobin levels) [6 months]
7. Serum albumin (Serum albumin levels) [6 months]
