14 ফলাফল
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]4-(2-carbamoyl-benzofuran-5-yl)-piperazine, its physiologically acceptable salts thereof
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl -benzofuran-5-yl)-piperazine, its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
FIELD OF THE INVENTION
The present invention relates to novel compounds, to processes for preparing them and to their use in treating medical disorders.
BACKGROUND OF THE INVENTION
1-[4-(5-Cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine- , its physiologically acceptable salts
The invention relates to substituted benzofuran-2-carboxamides of the formula I
##STR00002## in which D is H, OH, OA, CN, Hal, COR.sup.3 or CH.sub.2R.sup.3, R.sup.1 is amino, hydroxyl, cyano, --C(.dbd.NR.sup.4)--N(R.sup.4).sub.2, Het, unsubstituted or A-substituted cycloalkyl having from 3 to 10
FIELD OF THE INVENTION
The invention relates to leptin peptide fragments and their use as agonists of the leptin receptor.
BACKGROUND OF THE INVENTION
Leptin is a neurohormone that acts in the hypothalamus to regulate energy balance and food intake (M. Wauters, et al., Eur. J. Endocrinol., 2000,
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Jul. 3, 2012, is named 1320USPR.txt and is 450,377 bytes in size.
BACKGROUND OF THE
FIELD OF INVENTION
The invention relates to leptin agonists and their use in treatment of obesity and metabolic diseases.
BACKGROUND OF THE INVENTION
Leptin is a neurohormone that acts in the hypothalamus to regulate energy balance and food intake (amino acid sequence SEQ ID NO:1; Wauters et al.,