3 ফলাফল
Primary Objective
Phase Ib: To determine the safety and tolerability of Y-90 radioembolization therapy when given in conjunction with neoadjuvant/adjuvant nivolumab as assessed by CTCAE version 4, in patients with metastatic colorectal cancer who undergo Y-90 radioembolization to hepatic metastases
Clinical study Evaluation of oncological treatment response in patients with non-resectable colorectal liver metastases based on microscopic tissue analyses obtained by a minimal invasive technique.
Background The incidence of colorectal cancer (CRC) in Denmark is 4.200 cases and the prevalence is
PRIMARY OBJECTIVES:
I. To identify MTD of nivolumab for combination treatment of nivolumab and Y-90 in this population.
SECONDARY OBJECTIVES:
I. To evaluate the proportion of patients with objective response rate (ORR) (according to Response Evaluation Criteria in Solid Tumors [RECIST] criteria) to